IUBMB Enzyme Nomenclature


Accepted name: phenylalanine dehydrogenase

Reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH + H+

Other name(s): L-phenylalanine dehydrogenase; PHD

Systematic name: L-phenylalanine:NAD+ oxidoreductase (deaminating)

Comments: The enzymes from Bacillus badius and Sporosarcina ureae are highly specific for L-phenylalanine; that from Bacillus sphaericus also acts on L-tyrosine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 69403-12-9


1. Asano, Y., Nakazawa, A. and Endo, K. Novel phenylalanine dehydrogenases from Sporosarcina ureae and Bacillus sphaericus. Purification and characterization. J. Biol. Chem. 262 (1987) 10346-10354. [PMID: 3112142]

2. Asano, Y., Nakazawa, A., Endo, K., Hibino, Y., Ohmori, M., Numao, N. and Kondo, K. Phenylalanine dehydrogenase of Bacillus badius. Purification, characterization and gene cloning. Eur. J. Biochem. 168 (1987) 153-159. [PMID: 3311741]

[EC created 1989]

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