Reaction: (1) D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2
(2) D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2
Other name(s): D-glutamic-aspartic oxidase; D-monoaminodicarboxylic acid oxidase
Systematic name: D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)
Comments: A flavoprotein (FAD). D-Glutamate and D-aspartate are oxidized at the same rate. Other D-monoaminodicarboxylates, and other D- and L-amino acids, are not oxidized. cf. EC 18.104.22.168, D-glutamate oxidase and EC 22.214.171.124, D-aspartate oxidase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9029-20-3
1. Mizushima, S. Purified D-glutamic-aspartic oxidase of Aspergillus ustus. J. Gen. Appl. Microbiol. 3 (1957) 233-239.