Reaction: N2-(D-1-carboxyethyl)-L-lysine + NADP+ + H2O = L-lysine + pyruvate + NADPH + H+
Other name(s): D-lysopine synthase; lysopine dehydrogenase; D(+)-lysopine dehydrogenase
Systematic name: N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)
Comments: In the reverse reaction, a number of L-amino acids can act instead of L-lysine, and 2-oxobutanoate and, to a lesser extent, glyoxylate can act instead of pyruvate.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 65187-41-9
1. Otten, L.A.B.M., Vreugdenhil, D. and Schilperoort, R.A. Properties of D(+)-lysopine dehydrogenase from crown gall tumour tissue. Biochim. Biophys. Acta 485 (1977) 268-277. [PMID: 21695]