IUBMB Enzyme Nomenclature

EC 1.5.3.5

Accepted name: (S)-6-hydroxynicotine oxidase

Reaction: (S)-6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2

For diagram click here.

Other name(s): L-6-hydroxynicotine oxidase; 6-hydroxy-L-nicotine oxidase; 6-hydroxy-L-nicotine:oxygen oxidoreductase

Systematic name: (S)-6-hydroxynicotine:oxygen oxidoreductase

Comments: A flavoprotein (FAD).

Links to other databases: BRENDA, EXPASY, KEGG, UM-BBD, CAS registry number: 37256-29-4

References:

1. Dai, V.D., Decker, K. and Sund, H. Purification and properties of L-6-hydroxynicotine oxidase. Eur. J. Biochem. 4 (1968) 95-102. [PMID: 5646150]

2. Decker, K. and Bleeg, H. Induction and purification of stereospecific nicotine oxidizing enzymes from Arthrobacter oxidans. Biochim. Biophys. Acta 105 (1965) 313-324. [PMID: 5849820]

[EC 1.5.3.5 created 1972]


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