IUBMB Enzyme Nomenclature


Accepted name: L-pipecolate oxidase

Reaction: L-pipecolate + O2 = (S)-2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2

Glossary: L-1-piperideine 6-carboxylate = (S)-2,3,4,5-tetrahydropyridine-2-carboxylate = (S)-1,6-didehydropiperidine-2-carboxylate
(S)-2-amino-6-oxohexanoate = L-2-aminoadipate 6-semialdehyde = L-allysine

Other name(s): pipecolate oxidase; L-pipecolic acid oxidase

Systematic name: L-pipecolate:oxygen 1,6-oxidoreductase

Comments: The product reacts with water to form 2-aminoadipate 6-semialdehyde, i.e. 2-amino-6-oxohexanoate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 81669-65-0


1. Baginsky, B.L. and Rodwell, V.W. Metabolism of pipecolic acid in a Pseudomonas species. V. Pipecolate oxidase and dehydrogenase. J. Bacteriol. 94 (1967) 1034-1039. [PMID: 6051341]

2. Kinzel, J.J. and Bhattacharjee, J.K. Lysine biosynthesis in Rhodotorula glutinis: properties of pipecolic acid oxidase. J. Bacteriol. 151 (1982) 1073-1077. [PMID: 6809728]

[EC created 1986]

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