IUBMB Enzyme Nomenclature

EC 1.5.99.2

Accepted name: dimethylglycine dehydrogenase

Reaction: N,N-dimethylglycine + acceptor + H2O = sarcosine + formaldehyde + reduced acceptor

Other name(s): N,N-dimethylglycine oxidase; N,N-dimethylglycine:(acceptor) oxidoreductase (demethylating)

Systematic name: N,N-dimethylglycine:acceptor oxidoreductase (demethylating)

Comments: A flavoprotein.

Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 37256-30-7

References:

1. Frisell, W.R. and MacKenzie, C.G. Separation and purification of sarcosine dehydrogenase and dimethylglycine dehydrogenase. J. Biol. Chem. 237 (1962) 94-98.

2. Hoskins, D.D. and MacKenzie, C.G. Solubilization and electron transfer flavoprotein requirement of mitochondrial sarcosine dehydrogenase and dimethylglycine dehydrogenase. J. Biol. Chem. 236 (1961) 177-183.

[EC 1.5.99.2 created 1972]


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