Reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+
Other name(s): nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)); NADH-nitrite oxidoreductase; NADPH-nitrite reductase; assimilatory nitrite reductase; nitrite reductase [NAD(P)H2]; NAD(P)H2:nitrite oxidoreductase
Systematic name: ammonium-hydroxide:NAD(P)+ oxidoreductase
Comments: An iron-sulfur heme flavoprotein containing siroheme.
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 9029-29-2
References:
1. Cammack, R., Jackson, R.H., Cornish-Bowden, A. and Cole, J.A. Electron-spin-resonance studies of the NADH-dependent nitrite reductase from Escherichia coli K12. Biochem. J. 207 (1982) 333-339. [PMID: 6297458]
2. Lazzarini, R.A. and Atkinson, D.E. A triphosphopyridine nucleotide-specific nitrite reductase from Escherichia coli. J. Biol. Chem. 236 (1961) 3330-3335.
3. Nicholas, D.J.D., Medina, A. and Jones, O.T.G. A nitrite reductase from Neurospora crassa. Biochim. Biophys. Acta 37 (1960) 468.
4. Taniguchi, H., Mitsui, H., Nakamura, K. and Egami, F. Ann. Acad. Sci. Fenn. Ser. A II 60 (1955) 200.
5. Colandene, J.D. and Garrett, R.H. Functional dissection and site-directed mutagenesis of the structural gene for NAD(P)H-nitrite reductase in Neurospora crassa. J. Biol. Chem. 271 (1996) 24096-24104. [PMID: 8798648]