IUBMB Enzyme Nomenclature

EC 1.7.99.4

Accepted name: nitrate reductase

Reaction: nitrite + acceptor = nitrate + reduced acceptor

Other name(s): respiratory nitrate reductase; nitrate reductase (acceptor); nitrite:(acceptor) oxidoreductase

Systematic name: nitrite:acceptor oxidoreductase

Comments: The Pseudomonas enzyme is a cytochrome, but the enzyme from Micrococcus halodenitrificans is an iron protein containing molybdenum. Reduced benzyl viologen and other dyes bring about the reduction of nitrate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37256-45-4

References:

1. Nason, A. Nitrate reductase, In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 587-607.

2. Radcliffe, B.C. and Nicholas, D.J.D. Some properties of a nitrate reductase from Pseudomonas denitrificans. Biochim. Biophys. Acta 205 (1970) 273-287. [PMID: 4316095]

3. Rosso, J.-P., Forget, P. and Pichinoty, F. Les nitrate-réductases bactériennes solubilisation, purification et propriétés de l'enzyme A de Micrococcus halodenitrificans. Biochim. Biophys. Acta 321 (1973) 443-455. [PMID: 4762405]

[EC 1.7.99.4 created 1972, modified 1976]


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