IUBMB Enzyme Nomenclature


Accepted name: cystine reductase

Reaction: 2 L-cysteine + NAD+ = L-cystine + NADH + H+

Other name(s): cystine reductase (NADH); NADH-dependent cystine reductase; cystine reductase (NADH2); NADH2:L-cystine oxidoreductase

Systematic name: L-cysteine:NAD+ oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9029-18-9


1. Romano, A.H. and Nickerson, W.J. Cystine reductase of pea seeds and yeast. J. Biol. Chem. 208 (1954) 409-416.

2. Carroll, J.E., Kosicki, G.W. and Thibert, R.J. α-Substituted cystines as possible substrates for cystine reductase and L-amino acid oxidase. Biochim. Biophys. Acta 198 (1970) 601-603. [PMID: 5436160]

3. Maresca, B., Jacobson, E., Medoff, G. and Kobayashi, G. Cystine reductase in the dimorphic fungus Histoplasma capsulatum. J. Bacteriol. 135 (1978) 987-992. [PMID: 211119]

[EC created 1961 as EC, transferred 2002 to EC]

Return to EC 1.8.1 home page
Return to EC 1.8 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page