IUBMB Enzyme Nomenclature


Accepted name: protein-disulfide reductase

Reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+

Other name(s): protein disulphide reductase; insulin-glutathione transhydrogenase; disulfide reductase; NAD(P)H2:protein-disulfide oxidoreductase

Systematic name: protein-dithiol:NAD(P)+ oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9029-19-0


1. Hatch, M.D. and Turner, J.F. A protein disulphide reductase from pea seeds. Biochem. J. 76 (1960) 556-562.

[EC created 1965 as EC, transferred 2002 to EC]

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