Reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor
methyl viologen = 1,1'-dimethyl-4,4'-bipyridinium
Other name(s): tetrachloroethene reductase
Systematic name: acceptor:trichloroethene oxidoreductase (chlorinating)
Comments: This enzyme allows the common pollutant tetrachloroethene to support bacterial growth and is responsible for disposal of a number of chlorinated hydrocarbons by this organism. The reaction occurs in the reverse direction. The enzyme also reduces trichloroethene to dichloroethene. Although the physiological reductant is unknown, the supply of reductant in some organisms is via reduced menaquinone, itself formed from molecular hydrogen, via EC 220.127.116.11 (hydrogen:quinone oxidoreductase). The enzyme contains a corrinoid and two iron-sulfur clusters. Methyl viologen can act as electron donor.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 163913-51-7
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