Nomenclature Committee of the
International Union of Biochemistry and Molecular Biology (NC-IUBMB)

Enzyme Nomenclature

Contents

EC 1 Oxidoreductases

EC 1.1 Acting on the CH-OH group of donors

EC 1.1.1 With NAD+ or NADP+ as acceptor

EC 1.1.1.1 alcohol dehydrogenase
EC 1.1.1.2 alcohol dehydrogenase (NADP+)
EC 1.1.1.3 homoserine dehydrogenase
EC 1.1.1.4 (R,R)-butanediol dehydrogenase
EC 1.1.1.5 transferred, now EC 1.1.1.303 and EC 1.1.1.304
EC 1.1.1.6 glycerol dehydrogenase
EC 1.1.1.7 propanediol-phosphate dehydrogenase
EC 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+)
EC 1.1.1.9 D-xylulose reductase
EC 1.1.1.10 L-xylulose reductase
EC 1.1.1.11 D-arabinitol 4-dehydrogenase
EC 1.1.1.12 L-arabinitol 4-dehydrogenase
EC 1.1.1.13 L-arabinitol 2-dehydrogenase
EC 1.1.1.14 L-iditol 2-dehydrogenase
EC 1.1.1.15 D-iditol 2-dehydrogenase
EC 1.1.1.16 galactitol 2-dehydrogenase
EC 1.1.1.17 mannitol-1-phosphate 5-dehydrogenase
EC 1.1.1.18 inositol 2-dehydrogenase
EC 1.1.1.19 glucuronate reductase
EC 1.1.1.20 glucuronolactone reductase
EC 1.1.1.21 aldehyde reductase
EC 1.1.1.22 UDP-glucose 6-dehydrogenase
EC 1.1.1.23 histidinol dehydrogenase
EC 1.1.1.24 quinate dehydrogenase
EC 1.1.1.25 shikimate dehydrogenase
EC 1.1.1.26 glyoxylate reductase
EC 1.1.1.27 L-lactate dehydrogenase
EC 1.1.1.28 D-lactate dehydrogenase
EC 1.1.1.29 glycerate dehydrogenase
EC 1.1.1.30 3-hydroxybutyrate dehydrogenase
EC 1.1.1.31 3-hydroxyisobutyrate dehydrogenase
EC 1.1.1.32 mevaldate reductase
EC 1.1.1.33 mevaldate reductase (NADPH)
EC 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
EC 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
EC 1.1.1.36 acetoacetyl-CoA reductase
EC 1.1.1.37 malate dehydrogenase
EC 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
EC 1.1.1.39 malate dehydrogenase (decarboxylating)
EC 1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
EC 1.1.1.41 isocitrate dehydrogenase (NAD+)
EC 1.1.1.42 isocitrate dehydrogenase (NADP+)
EC 1.1.1.43 phosphogluconate 2-dehydrogenase
EC 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
EC 1.1.1.45 L-gulonate 3-dehydrogenase
EC 1.1.1.46 L-arabinose 1-dehydrogenase
EC 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
EC 1.1.1.48 D-galactose 1-dehydrogenase
EC 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
EC 1.1.1.50 3α-hydroxysteroid 3-dehydrogenase (Si-specific)
EC 1.1.1.51 3(or 17)β-hydroxysteroid dehydrogenase
EC 1.1.1.52 3α-hydroxycholanate dehydrogenase (NAD+)
EC 1.1.1.53 3α(or 20β)-hydroxysteroid dehydrogenase
EC 1.1.1.54 allyl-alcohol dehydrogenase
EC 1.1.1.55 lactaldehyde reductase (NADPH)
EC 1.1.1.56 ribitol 2-dehydrogenase
EC 1.1.1.57 fructuronate reductase
EC 1.1.1.58 tagaturonate reductase
EC 1.1.1.59 3-hydroxypropionate dehydrogenase
EC 1.1.1.60 2-hydroxy-3-oxopropionate reductase
EC 1.1.1.61 4-hydroxybutyrate dehydrogenase
EC 1.1.1.62 17β-estradiol 17-dehydrogenase
EC 1.1.1.63 testosterone 17β-dehydrogenase
EC 1.1.1.63 transferred, now EC 1.1.1.239
EC 1.1.1.64 testosterone 17β-dehydrogenase (NADP+)
EC 1.1.1.65 pyridoxine 4-dehydrogenase
EC 1.1.1.66 ω-hydroxydecanoate dehydrogenase
EC 1.1.1.67 mannitol 2-dehydrogenase
EC 1.1.1.68 now EC 1.7.99.5
EC 1.1.1.69 gluconate 5-dehydrogenase
EC 1.1.1.70 deleted, included in EC 1.2.1.3
EC 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
EC 1.1.1.72 glycerol dehydrogenase (NADP+)
EC 1.1.1.73 octanol dehydrogenase
EC 1.1.1.74 deleted
EC 1.1.1.75 (R)-aminopropanal dehydrogenase
EC 1.1.1.76 (S,S)-butanediol dehydrogenase
EC 1.1.1.77 lactaldehyde reductase
EC 1.1.1.78 methylglyoxal reductase (NADH)
EC 1.1.1.79 glyoxylate reductase (NADP+)
EC 1.1.1.80 isopropanol dehydrogenase (NADP+)
EC 1.1.1.81 hydroxypyruvate reductase
EC 1.1.1.82 malate dehydrogenase (NADP+)
EC 1.1.1.83 D-malate dehydrogenase (decarboxylating)
EC 1.1.1.84 dimethylmalate dehydrogenase
EC 1.1.1.85 3-isopropylmalate dehydrogenase
EC 1.1.1.86 ketol-acid reductoisomerase (NADP+)
EC 1.1.1.87 homoisocitrate dehydrogenase
EC 1.1.1.88 hydroxymethylglutaryl-CoA reductase
EC 1.1.1.89 deleted, included in EC 1.1.1.86
EC 1.1.1.90 aryl-alcohol dehydrogenase
EC 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
EC 1.1.1.92 oxaloglycolate reductase (decarboxylating)
EC 1.1.1.93 tartrate dehydrogenase
EC 1.1.1.94 glycerol-3-phosphate dehydrogenase [NAD(P)+]
EC 1.1.1.95 phosphoglycerate dehydrogenase
EC 1.1.1.96 diiodophenylpyruvate reductase
EC 1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
EC 1.1.1.98 (R)-2-hydroxy-fatty-acid dehydrogenase
EC 1.1.1.99 (S)-2-hydroxy-fatty-acid dehydrogenase
EC 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
EC 1.1.1.101 acylglycerone-phosphate reductase
EC 1.1.1.102 3-dehydrosphinganine reductase
EC 1.1.1.103 L-threonine 3-dehydrogenase
EC 1.1.1.104 4-oxoproline reductase
EC 1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
EC 1.1.1.106 pantoate 4-dehydrogenase
EC 1.1.1.107 pyridoxal 4-dehydrogenase
EC 1.1.1.108 carnitine 3-dehydrogenase
EC 1.1.1.109 now EC 1.3.1.28
EC 1.1.1.110 indolelactate dehydrogenase
EC 1.1.1.111 3-(imidazol-5-yl)lactate dehydrogenase
EC 1.1.1.112 indanol dehydrogenase
EC 1.1.1.113 L-xylose 1-dehydrogenase
EC 1.1.1.114 apiose 1-reductase
EC 1.1.1.115 ribose 1-dehydrogenase (NADP+)
EC 1.1.1.116 D-arabinose 1-dehydrogenase (NAD+)
EC 1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
EC 1.1.1.118 glucose 1-dehydrogenase (NAD+)
EC 1.1.1.119 glucose 1-dehydrogenase (NADP+)
EC 1.1.1.120 galactose 1-dehydrogenase (NADP+)
EC 1.1.1.121 aldose 1-dehydrogenase (NAD+)
EC 1.1.1.122 D-threo-aldose 1-dehydrogenase
EC 1.1.1.123 sorbose 5-dehydrogenase (NADP+)
EC 1.1.1.124 fructose 5-dehydrogenase (NADP+)
EC 1.1.1.125 2-deoxy-D-gluconate 3-dehydrogenase
EC 1.1.1.126 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
EC 1.1.1.127 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
EC 1.1.1.128 deleted covered by EC 1.1.1.264
EC 1.1.1.129 L-threonate 3-dehydrogenase
EC 1.1.1.130 3-dehydro-L-gulonate 2-dehydrogenase
EC 1.1.1.131 mannuronate reductase
EC 1.1.1.132 GDP-mannose 6-dehydrogenase
EC 1.1.1.133 dTDP-4-dehydrorhamnose reductase
EC 1.1.1.134 dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+)
EC 1.1.1.135 GDP-6-deoxy-D-talose 4-dehydrogenase
EC 1.1.1.136 UDP-N-acetylglucosamine 6-dehydrogenase
EC 1.1.1.137 ribitol-5-phosphate 2-dehydrogenase
*EC 1.1.1.137 ribitol-5-phosphate 2-dehydrogenase
EC 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
EC 1.1.1.139 deleted, included in EC 1.1.1.21
EC 1.1.1.140 sorbitol-6-phosphate 2-dehydrogenase
EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+)
EC 1.1.1.142 D-pinitol dehydrogenase
EC 1.1.1.143 sequoyitol dehydrogenase
EC 1.1.1.144 perillyl-alcohol dehydrogenase
EC 1.1.1.145 3β-hydroxy-Δ5-steroid dehydrogenase
EC 1.1.1.146 11β-hydroxysteroid dehydrogenase
EC 1.1.1.147 16α-hydroxysteroid dehydrogenase
EC 1.1.1.148 estradiol 17α-dehydrogenase
EC 1.1.1.149 20α-hydroxysteroid dehydrogenase
EC 1.1.1.150 21-hydroxysteroid dehydrogenase (NAD+)
EC 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
EC 1.1.1.152 3α-hydroxy-5β-androstane-17-one 3α-dehydrogenase
EC 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
EC 1.1.1.154 ureidoglycolate dehydrogenase
EC 1.1.1.155 identical to EC 1.1.1.87
EC 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
EC 1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase
EC 1.1.1.158 transferred now EC 1.3.1.98
EC 1.1.1.159 7α-hydroxysteroid dehydrogenase
EC 1.1.1.160 dihydrobunolol dehydrogenase
EC 1.1.1.161 deleted, covered by EC 1.14.13.15
EC 1.1.1.162 erythrulose reductase
EC 1.1.1.163 cyclopentanol dehydrogenase
EC 1.1.1.164 hexadecanol dehydrogenase
EC 1.1.1.165 2-alkyn-1-ol dehydrogenase
EC 1.1.1.166 hydroxycyclohexanecarboxylate dehydrogenase
EC 1.1.1.167 hydroxymalonate dehydrogenase
EC 1.1.1.168 2-dehydropantolactone reductase (Re-specific)
EC 1.1.1.169 2-dehydropantoate 2-reductase
EC 1.1.1.170 3β-hydroxy-4α-carboxy-sterol 3-dehydrogenase (decarboxylating)
EC 1.1.1.171 now EC 1.5.1.20
EC 1.1.1.172 2-oxoadipate reductase
EC 1.1.1.173 L-rhamnose 1-dehydrogenase
EC 1.1.1.174 cyclohexane-1,2-diol dehydrogenase
EC 1.1.1.175 D-xylose 1-dehydrogenase
EC 1.1.1.176 12α-hydroxysteroid dehydrogenase
EC 1.1.1.177 glycerol-3-phosphate 1-dehydrogenase (NADP+)
EC 1.1.1.178 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
EC 1.1.1.179 D-xylose 1-dehydrogenase (NADP+)
EC 1.1.1.180 deleted, included in EC 1.1.1.131
EC 1.1.1.181 cholest-5-ene-3β,7α-diol 3β-dehydrogenase
EC 1.1.1.182 deleted, included in EC 1.1.1.198, EC 1.1.1.227 and EC 1.1.1.228
EC 1.1.1.183 geraniol dehydrogenase
EC 1.1.1.184 carbonyl reductase (NADPH)
EC 1.1.1.185 L-glycol dehydrogenase
EC 1.1.1.186 dTDP-galactose 6-dehydrogenase
EC 1.1.1.187 GDP-4-dehydro-D-rhamnose reductase
EC 1.1.1.188 prostaglandin-F synthase
EC 1.1.1.189 prostaglandin-E2 9-reductase
EC 1.1.1.190 indole-3-acetaldehyde reductase (NADH)
EC 1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
EC 1.1.1.192 long-chain-alcohol dehydrogenase
EC 1.1.1.193 5-amino-6-(5-phosphoribosylamino)uracil reductase
EC 1.1.1.194 coniferyl-alcohol dehydrogenase
EC 1.1.1.195 cinnamyl-alcohol dehydrogenase
EC 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
EC 1.1.1.198 (+)-borneol dehydrogenase
EC 1.1.1.199 (S)-usnate reductase
EC 1.1.1.200 aldose-6-phosphate reductase (NADPH)
EC 1.1.1.201 7β-hydroxysteroid dehydrogenase (NADP+)
EC 1.1.1.202 1,3-propanediol dehydrogenase
EC 1.1.1.203 uronate dehydrogenase
EC 1.1.1.204 now EC 1.17.1.4
EC 1.1.1.205 IMP dehydrogenase
EC 1.1.1.206 tropinone reductase I
EC 1.1.1.207 (–)-menthol dehydrogenase
EC 1.1.1.208 (+)-neomenthol dehydrogenase
EC 1.1.1.209 3(or 17)α-hydroxysteroid dehydrogenase
EC 1.1.1.210 3β(or 20α)-hydroxysteroid dehydrogenase
EC 1.1.1.211 long-chain-3-hydroxyacyl-CoA dehydrogenase
EC 1.1.1.212 3-oxoacyl-[acyl-carrier-protein] reductase (NADH)
EC 1.1.1.213 3α-hydroxysteroid 3-dehydrogenase (Re-specific)
EC 1.1.1.214 2-dehydropantolactone reductase (Si-specific)
EC 1.1.1.215 gluconate 2-dehydrogenase
EC 1.1.1.216 farnesol dehydrogenase
EC 1.1.1.217 benzyl-2-methyl-hydroxybutyrate dehydrogenase
EC 1.1.1.218 morphine 6-dehydrogenase
EC 1.1.1.219 dihydroflavonol 4-reductase
EC 1.1.1.220 6-pyruvoyltetrahydropterin 2'-reductase
EC 1.1.1.221 vomifoliol 4'-dehydrogenase
EC 1.1.1.222 (R)-4-hydroxyphenyllactate dehydrogenase
EC 1.1.1.223 isopiperitenol dehydrogenase
EC 1.1.1.224 mannose-6-phosphate 6-reductase
EC 1.1.1.225 chlordecone reductase
EC 1.1.1.226 4-hydroxycyclohexanecarboxylate dehydrogenase
EC 1.1.1.227 (–)-borneol dehydrogenase
EC 1.1.1.228 (+)-sabinol dehydrogenase
EC 1.1.1.229 diethyl 2-methyl-3-oxosuccinate reductase
EC 1.1.1.230 3α-hydroxyglycyrrhetinate dehydrogenase
EC 1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
EC 1.1.1.232 15-hydroxyicosatetraenoate dehydrogenase
EC 1.1.1.233 N-acylmannosamine 1-dehydrogenase
EC 1.1.1.234 flavanone 4-reductase
EC 1.1.1.235 8-oxocoformycin reductase
EC 1.1.1.236 tropinone reductase II
EC 1.1.1.237 hydroxyphenylpyruvate reductase
EC 1.1.1.238 12β-hydroxysteroid dehydrogenase
EC 1.1.1.239 3α(17β)-hydroxysteroid dehydrogenase (NAD+)
EC 1.1.1.240 N-acetylhexosamine 1-dehydrogenase
EC 1.1.1.241 6-endo-hydroxycineole dehydrogenase
EC 1.1.1.242 now EC 1.3.1.69 zeatin reductase
EC 1.1.1.243 carveol dehydrogenase
EC 1.1.1.244 methanol dehydrogenase
EC 1.1.1.245 cyclohexanol dehydrogenase
EC 1.1.1.246 transferred now EC 1.1.1.348 and EC 4.2.1.139
EC 1.1.1.247 codeinone reductase (NADPH)
EC 1.1.1.248 salutaridine reductase (NADPH)
EC 1.1.1.249 reinstated as EC 2.5.1.46
EC 1.1.1.250 D-arabinitol 2-dehydrogenase
EC 1.1.1.251 galactitol-1-phosphate 5-dehydrogenase
EC 1.1.1.252 tetrahydroxynaphthalene reductase
EC 1.1.1.253 now EC 1.5.1.33
EC 1.1.1.254 (S)-carnitine 3-dehydrogenase
EC 1.1.1.255 mannitol dehydrogenase
EC 1.1.1.256 fluoren-9-ol dehydrogenase
EC 1.1.1.257 4-(hydroxymethyl)benzenesulfonate dehydrogenase
EC 1.1.1.258 6-hydroxyhexanoate dehydrogenase
EC 1.1.1.259 3-hydroxypimeloyl-CoA dehydrogenase
EC 1.1.1.260 sulcatone reductase
EC 1.1.1.261 sn-glycerol-1-phosphate dehydrogenase
EC 1.1.1.262 4-hydroxythreonine-4-phosphate dehydrogenase
EC 1.1.1.263 1,5-anhydro-D-fructose reductase
EC 1.1.1.264 L-idonate 5-dehydrogenase [NAD(P)+]
EC 1.1.1.265 3-methylbutanal reductase
EC 1.1.1.266 dTDP-4-dehydro-6-deoxyglucose reductase (NADPH)
EC 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase
EC 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase
EC 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase
EC 1.1.1.270 3β-hydroxysteroid 3-dehydrogenase
EC 1.1.1.271 GDP-L-fucose synthase
EC 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
EC 1.1.1.273 vellosimine dehydrogenase
EC 1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
EC 1.1.1.275 (+)-trans-carveol dehydrogenase
EC 1.1.1.276 serine 3-dehydrogenase (NADP+)
EC 1.1.1.277 3β-hydroxy-5β-steroid dehydrogenase
EC 1.1.1.278 3β-hydroxy-5α-steroid dehydrogenase
EC 1.1.1.279 (R)-3-hydroxyacid ester dehydrogenase
EC 1.1.1.280 (S)-3-hydroxyacid ester dehydrogenase
EC 1.1.1.281 GDP-4-dehydro-6-deoxy-D-mannose reductase
EC 1.1.1.282 quinate/shikimate dehydrogenase
EC 1.1.1.283 methylglyoxal reductase (NADPH)
EC 1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase
EC 1.1.1.285 3"-deamino-3"-oxonicotianamine reductase
EC 1.1.1.286 isocitrate—homoisocitrate dehydrogenase
EC 1.1.1.287 D-arabinitol dehydrogenase (NADP+)
EC 1.1.1.288 xanthoxin dehydrogenase
EC 1.1.1.289 sorbose reductase
EC 1.1.1.290 4-phosphoerythronate dehydrogenase
EC 1.1.1.291 2-hydroxymethylglutarate dehydrogenase
EC 1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
EC 1.1.1.293 deleted, identical to EC 1.1.1.206
EC 1.1.1.294 chlorophyll(ide) b reductase
EC 1.1.1.295 momilactone-A synthase
EC 1.1.1.296 dihydrocarveol dehydrogenase
EC 1.1.1.297 limonene-1,2-diol dehydrogenase
EC 1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)
EC 1.1.1.299 malate dehydrogenase [NAD(P)+]
EC 1.1.1.300 NADP-retinol dehydrogenase
EC 1.1.1.301 D-arabitol-phosphate dehydrogenase
EC 1.1.1.302 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
EC 1.1.1.303 diacetyl reductase [(R)-acetoin forming]
EC 1.1.1.304 diacetyl reductase [(S)-acetoin forming]
EC 1.1.1.305 UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)
EC 1.1.1.306 S-(hydroxymethyl)mycothiol dehydrogenase
EC 1.1.1.307 D-xylose reductase
EC 1.1.1.308 sulfopropanediol 3-dehydrogenase
EC 1.1.1.309 phosphonoacetaldehyde reductase (NADH)
EC 1.1.1.310 (S)-sulfolactate dehydrogenase
EC 1.1.1.311 (S)-1-phenylethanol dehydrogenase
EC 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
EC 1.1.1.313 sulfoacetaldehyde reductase
EC 1.1.1.314 germacrene A alcohol dehydrogenase
EC 1.1.1.315 11-cis-retinol dehydrogenase
EC 1.1.1.316 L-galactose 1-dehydrogenase
EC 1.1.1.317 perakine reductase
EC 1.1.1.318 eugenol synthase
EC 1.1.1.319 isoeugenol synthase
EC 1.1.1.320 benzil reductase [(S)-benzoin forming]
EC 1.1.1.321 benzil reductase [(R)-benzoin forming]
EC 1.1.1.322 (–)-endo-fenchol dehydrogenase
EC 1.1.1.323 (+)-thujan-3-ol dehydrogenase
EC 1.1.1.324 8-hydroxygeraniol dehydrogenase
EC 1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
EC 1.1.1.326 zerumbone synthase
EC 1.1.1.327 5-exo-hydroxycamphor dehydrogenase
EC 1.1.1.328 nicotine blue oxidoreductase
EC 1.1.1.329 2-deoxy-scyllo-inosamine dehydrogenase
EC 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
EC 1.1.1.331 secoisolariciresinol dehydrogenase
EC 1.1.1.332 chanoclavine-I dehydrogenase
EC 1.1.1.333 decaprenylphospho-β-D-erythro-pentofuranosid-2-ulose 2-reductase
EC 1.1.1.334 methylecgonone reductase
EC 1.1.1.335 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
EC 1.1.1.336 UDP-N-acetyl-D-mannosamine dehydrogenase
EC 1.1.1.337 L-2-hydroxycarboxylate dehydrogenase (NAD+)
EC 1.1.1.338 (2R)-3-sulfolactate dehydrogenase (NADP+)
EC 1.1.1.339 dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+)
EC 1.1.1.340 1-deoxy-11β-hydroxypentalenate dehydrogenase
EC 1.1.1.341 CDP-abequose synthase
EC 1.1.1.342 CDP-paratose synthase
EC 1.1.1.343 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)
EC 1.1.1.344 dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+]
EC 1.1.1.345 D-2-hydroxyacid dehydrogenase (NAD+)
EC 1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
EC 1.1.1.347 geraniol dehydrogenase (NAD+)
EC 1.1.1.348 vestitone reductase
EC 1.1.1.349 norsolorinic acid ketoreductase
EC 1.1.1.350 ureidoglycolate dehydrogenase (NAD+)
EC 1.1.1.351 phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
EC 1.1.1.352 5'-hydroxyaverantin dehydrogenase
EC 1.1.1.353 versiconal hemiacetal acetate reductase
EC 1.1.1.354 farnesol dehydrogenase (NAD+)
EC 1.1.1.355 2'-dehydrokanamycin reductase
EC 1.1.1.356 GDP-L-colitose synthase
EC 1.1.1.357 3α-hydroxysteroid 3-dehydrogenase
EC 1.1.1.358 2-dehydropantolactone reductase
EC 1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
EC 1.1.1.360 glucose/galactose 1-dehydrogenase
EC 1.1.1.361 glucose-6-phosphate 3-dehydrogenase
EC 1.1.1.362 aklaviketone reductase
EC 1.1.1.363 glucose-6-phosphate dehydrogenase [NAD(P)+]
EC 1.1.1.364 dTDP-4-dehydro-6-deoxy-α-D-gulose 4-ketoreductase
EC 1.1.1.365 D-galacturonate reductase
EC 1.1.1.366 L-idonate 5-dehydrogenase (NAD+)
EC 1.1.1.367 UDP-2-acetamido-2,6-β-L-arabino-hexul-4-ose reductase
EC 1.1.1.368 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
EC 1.1.1.369 D-chiro-inositol 1-dehydrogenase
EC 1.1.1.370 scyllo-inositol 2-dehydrogenase (NAD+)
EC 1.1.1.371 scyllo-inositol 2-dehydrogenase (NADP+)
EC 1.1.1.372 D/L-glyceraldehyde reductase
EC 1.1.1.373 sulfolactaldehyde 3-reductase
EC 1.1.1.374 UDP-N-acetylglucosamine 3-dehydrogenase
EC 1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
EC 1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
EC 1.1.1.377 L-rhamnose 1-dehydrogenase (NADP+)
EC 1.1.1.378 L-rhamnose 1-dehydrogenase [NAD(P)+]
EC 1.1.1.379 (R)-mandelate dehydrogenase
EC 1.1.1.380 L-gulonate 5-dehydrogenase
EC 1.1.1.381 3-hydroxy acid dehydrogenase
EC 1.1.1.382 ketol-acid reductoisomerase (NAD+)
EC 1.1.1.383 ketol-acid reductoisomerase [NAD(P)+]
EC 1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose 3-reductase
EC 1.1.1.385 dihydroanticapsin dehydrogenase
EC 1.1.1.386 ipsdienol dehydrogenase
EC 1.1.1.387 L-serine 3-dehydrogenase (NAD+)
EC 1.1.1.388 glucose-6-phosphate dehydrogenase (NAD+)
EC 1.1.1.389 2-dehydro-3-deoxy-L-galactonate 5-dehydrogenase
EC 1.1.1.390 sulfoquinovose 1-dehydrogenase
EC 1.1.1.391 3β-hydroxycholanate 3-dehydrogenase (NAD+)
EC 1.1.1.392 3α-hydroxycholanate dehydrogenase (NADP+)
EC 1.1.1.393 3β-hydroxycholanate 3-dehydrogenase (NADP+)
EC 1.1.1.394 aurachin B dehydrogenase
EC 1.1.1.395 3α-hydroxy bile acid-CoA-ester 3-dehydrogenase
EC 1.1.1.396 bacteriochlorophyllide a dehydrogenase
EC 1.1.1.397 β-methylindole-3-pyruvate reductase
EC 1.1.1.398 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase
EC 1.1.1.399 2-oxoglutarate reductase
EC 1.1.1.400 2-methyl-1,2-propanediol dehydrogenase
EC 1.1.1.401 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+)
EC 1.1.1.402 D-erythritol 1-phosphate dehydrogenase
EC 1.1.1.403 D-threitol dehydrogenase (NAD+)
EC 1.1.1.404 tetrachlorobenzoquinone reductase
EC 1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+)
EC 1.1.1.406 galactitol 2-dehydrogenase (L-tagatose-forming)
EC 1.1.1.407 D-altritol 5-dehydrogenase
EC 1.1.2 With a cytochrome as acceptor
EC 1.1.2.1 now EC 1.1.99.5
EC 1.1.2.2 mannitol dehydrogenase (cytochrome)
EC 1.1.2.3 L-lactate dehydrogenase (cytochrome)
EC 1.1.2.4 D-lactate dehydrogenase (cytochrome)
EC 1.1.2.5 D-lactate dehydrogenase (cytochrome c-553)
EC 1.1.2.6 polyvinyl alcohol dehydrogenase (cytochrome)
EC 1.1.2.7 methanol dehydrogenase (cytochrome c)
EC 1.1.2.8 alcohol dehydrogenase (cytochrome c)
EC 1.1.2.9 1-butanol dehydrogenase (cytochrome c)
EC 1.1.3 With oxygen as acceptor
EC 1.1.3.1 deleted, included in EC 1.1.3.15
EC 1.1.3.2 now EC 1.13.12.4
EC 1.1.3.3 deleted now EC 1.1.5.4
EC 1.1.3.4 glucose oxidase
EC 1.1.3.5 hexose oxidase
EC 1.1.3.6 cholesterol oxidase
EC 1.1.3.7 aryl-alcohol oxidase
EC 1.1.3.8 L-gulonolactone oxidase
EC 1.1.3.9 galactose oxidase
EC 1.1.3.10 pyranose oxidase
EC 1.1.3.11 L-sorbose oxidase
EC 1.1.3.12 pyridoxine 4-oxidase
EC 1.1.3.13 alcohol oxidase
EC 1.1.3.14 catechol oxidase (dimerizing)
EC 1.1.3.15 (S)-2-hydroxy-acid oxidase
EC 1.1.3.16 ecdysone oxidase
EC 1.1.3.17 choline oxidase
EC 1.1.3.18 secondary-alcohol oxidase
EC 1.1.3.19 4-hydroxymandelate oxidase (decarboxylating)
EC 1.1.3.20 long-chain-alcohol oxidase
EC 1.1.3.21 glycerol-3-phosphate oxidase
EC 1.1.3.22 now EC 1.17.3.2
EC 1.1.3.23 thiamin oxidase
EC 1.1.3.24 now EC 1.3.3.12
EC 1.1.3.25 now included with EC 1.1.99.18
EC 1.1.3.26 now EC 1.21.3.2
EC 1.1.3.27 hydroxyphytanate oxidase
EC 1.1.3.28 nucleoside oxidase
EC 1.1.3.29 N-acylhexosamine oxidase
EC 1.1.3.30 polyvinyl-alcohol oxidase
EC 1.1.3.31 deleted
EC 1.1.3.32 now EC 1.14.21.1
EC 1.1.3.33 now EC 1.14.21.2
EC 1.1.3.34 now EC 1.14.21.3
EC 1.1.3.35 now EC 1.14.21.4
EC 1.1.3.36 now EC 1.14.21.5
EC 1.1.3.37 D-arabinono-1,4-lactone oxidase
EC 1.1.3.38 vanillyl-alcohol oxidase
EC 1.1.3.39 nucleoside oxidase (H2O2-forming)
EC 1.1.3.40 D-mannitol oxidase
EC 1.1.3.41 alditol oxidase
EC 1.1.3.42 prosolanapyrone-II oxidase
EC 1.1.3.43 paromamine 6'-oxidase
EC 1.1.3.44 6′′′-hydroxyneomycin C oxidase
EC 1.1.3.45 aclacinomycin-N oxidase
EC 1.1.3.46 4-hydroxymandelate oxidase
EC 1.1.3.47 5-(hydroxymethyl)furfural oxidase
EC 1.1.3.48 3-deoxy-α-D-manno-octulosonate 8-oxidase
EC 1.1.3.49 (R)-mandelonitrile oxidase
EC 1.1.4 With a disulfide as acceptor
EC 1.1.4.1 transferred, now EC 1.17.4.4
EC 1.1.4.2 transferred, now EC 1.17.4.5

EC 1.1.5 With a quinone or similar compound as acceptor

EC 1.1.5.1 deleted, see EC 1.1.99.18
EC 1.1.5.2 glucose 1-dehydrogenase (PQQ,quinone)
EC 1.1.5.3 glycerol-3-phosphate dehydrogenase
EC 1.1.5.4 malate dehydrogenase (quinone)
EC 1.1.5.5 alcohol dehydrogenase (quinone)
EC 1.1.5.6 formate dehydrogenase-N
EC 1.1.5.7 cyclic alcohol dehydrogenase (quinone)
EC 1.1.5.8 quinate dehydrogenase (quinone)
EC 1.1.5.9 glucose 1-dehydrogenase (FAD, quinone)
EC 1.1.5.10 D-2-hydroxyacid dehydrogenase (quinone)
EC 1.1.5.11 1-butanol dehydrogenase (quinone)
EC 1.1.5.12 D-lactate dehydrogenase (quinone)
EC 1.1.9 With a copper protein as acceptor
EC 1.1.9.1 alcohol dehydrogenase (azurin)
EC 1.1.98 With other, known, physiological acceptors
EC 1.1.98.1 transferred now EC 1.1.9.1 alcohol dehydrogenase (azurin)
EC 1.1.98.2 glucose-6-phosphate dehydrogenase (coenzyme-F420)
EC 1.1.98.3 decaprenylphospho-β-D-ribofuranose 2-oxidase
EC 1.1.98.4 F420H2:quinone oxidoreductase
EC 1.1.98.5 secondary-alcohol dehydrogenase (coenzyme-F420)
EC 1.1.98.6 ribonucleoside-triphosphate reductase (formate)
EC 1.1.99 With unknown physiological acceptors
EC 1.1.99.1 choline dehydrogenase
EC 1.1.99.2 L-2-hydroxyglutarate dehydrogenase
EC 1.1.99.3 gluconate 2-dehydrogenase (acceptor)
EC 1.1.99.4 dehydrogluconate dehydrogenase
EC 1.1.99.5 now EC 1.1.5.3
EC 1.1.99.5 glycerol-3-phosphate dehydrogenase
EC 1.1.99.6 D-lactate dehydrogenase (acceptor)
EC 1.1.99.7 lactate—malate transhydrogenase
EC 1.1.99.8 transferred now EC 1.1.2.7 and EC 1.1.2.8
EC 1.1.99.9 pyridoxine 5-dehydrogenase
EC 1.1.99.10 transferred now EC 1.1.5.9
EC 1.1.99.11 fructose 5-dehydrogenase
EC 1.1.99.12 sorbose dehydrogenase
EC 1.1.99.13 glucoside 3-dehydrogenase
EC 1.1.99.14 glycolate dehydrogenase
EC 1.1.99.15 now EC 1.7.99.5
EC 1.1.99.16 transferred now EC 1.1.5.4
EC 1.1.99.17 now EC 1.1.5.2
EC 1.1.99.18 cellobiose dehydrogenase (acceptor)
EC 1.1.99.19 deleted
EC 1.1.99.20 alkan-1-ol dehydrogenase (acceptor)
EC 1.1.99.21 D-sorbitol dehydrogenase (acceptor)
EC 1.1.99.22 glycerol dehydrogenase (acceptor)
EC 1.1.99.23 transferred now EC 1.1.2.6
EC 1.1.99.24 hydroxyacid-oxoacid transhydrogenase
EC 1.1.99.25 transferred now EC 1.1.5.8
EC 1.1.99.26 3-hydroxycyclohexanone dehydrogenase
EC 1.1.99.27 (R)-pantolactone dehydrogenase (flavin)
EC 1.1.99.28 glucose-fructose oxidoreductase EC 1.1.99.29 pyranose dehydrogenase (acceptor)
EC 1.1.99.30 2-oxoacid reductase
EC 1.1.99.31 (S)-mandelate dehydrogenase
EC 1.1.99.32 L-sorbose 1-dehydrogenase
EC 1.1.99.33 formate dehydrogenase (acceptor)
EC 1.1.99.34 transferred now EC 1.1.98.2
EC 1.1.99.35 soluble quinoprotein glucose dehydrogenase
EC 1.1.99.36 alcohol dehydrogenase (nicotinoprotein)
EC 1.1.99.37 methanol dehydrogenase (nicotinoprotein)
EC 1.1.99.38 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
EC 1.1.99.39 D-2-hydroxyglutarate dehydrogenase
EC 1.1.99.40 (R)-2-hydroxyglutarate—pyruvate transhydrogenase
EC 1.2 Acting on the aldehyde or oxo group of donors

EC 1.2.1 With NAD+ or NADP+ as acceptor

EC 1.2.1.1 deleted, replaced by EC 1.1.1.284 and EC 4.4.1.22
EC 1.2.1.2 formate dehydrogenase
EC 1.2.1.3 aldehyde dehydrogenase (NAD+)
EC 1.2.1.4 aldehyde dehydrogenase (NADP+)
EC 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
EC 1.2.1.6 deleted
EC 1.2.1.7 benzaldehyde dehydrogenase (NADP+)
EC 1.2.1.8 betaine-aldehyde dehydrogenase
EC 1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
EC 1.2.1.10 acetaldehyde dehydrogenase (acetylating)
EC 1.2.1.11 aspartate-semialdehyde dehydrogenase
EC 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
EC 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
EC 1.2.1.14 now EC 1.1.1.205
EC 1.2.1.15 malonate-semialdehyde dehydrogenase
EC 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
EC 1.2.1.17 glyoxylate dehydrogenase (acylating)
EC 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
EC 1.2.1.19 aminobutyraldehyde dehydrogenase
EC 1.2.1.20 glutarate-semialdehyde dehydrogenase
EC 1.2.1.21 glycolaldehyde dehydrogenase
EC 1.2.1.22 lactaldehyde dehydrogenase
EC 1.2.1.23 2-oxoaldehyde dehydrogenase (NAD+)
EC 1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
EC 1.2.1.25 2-oxoisovalerate dehydrogenase (acylating)
EC 1.2.1.26 2,5-dioxovalerate dehydrogenase
EC 1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
EC 1.2.1.28 benzaldehyde dehydrogenase (NAD+)
EC 1.2.1.29 aryl-aldehyde dehydrogenase
EC 1.2.1.30 aryl-aldehyde dehydrogenase (NADP+)
EC 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
EC 1.2.1.32 aminomuconate-semialdehyde dehydrogenase
EC 1.2.1.33 (R)-dehydropantoate dehydrogenase
EC 1.2.1.34 deleted, included in EC 1.1.1.131
EC 1.2.1.35 now EC 1.1.1.203
EC 1.2.1.36 retinal dehydrogenase
EC 1.2.1.37 now EC 1.1.1.204
EC 1.2.1.38 N-acetyl-γ-glutamyl-phosphate reductase
EC 1.2.1.39 phenylacetaldehyde dehydrogenase
EC 1.2.1.40 deleted, covered by EC 1.14.13.15
EC 1.2.1.41 glutamate-5-semialdehyde dehydrogenase
EC 1.2.1.42 hexadecanal dehydrogenase (acylating)
EC 1.2.1.43 formate dehydrogenase (NADP+)
EC 1.2.1.44 cinnamoyl-CoA reductase
EC 1.2.1.45 transferred now EC 1.1.1.312
EC 1.2.1.46 formaldehyde dehydrogenase
EC 1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase
EC 1.2.1.48 long-chain-aldehyde dehydrogenase
EC 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
EC 1.2.1.50 long-chain acyl-protein thioester reductase
EC 1.2.1.51 pyruvate dehydrogenase (NADP+)
EC 1.2.1.52 oxoglutarate dehydrogenase (NADP+)
EC 1.2.1.53 4-hydroxyphenylacetaldehyde dehydrogenase
EC 1.2.1.54 γ-guanidinobutyraldehyde dehydrogenase
EC 1.2.1.55 now EC 1.1.1.279
EC 1.2.1.56 now EC 1.1.1.280
EC 1.2.1.57 butanal dehydrogenase
EC 1.2.1.58 phenylglyoxylate dehydrogenase (acylating)
EC 1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)
EC 1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
EC 1.2.1.61 4-hydroxymuconic semialdehyde dehydrogenase
EC 1.2.1.62 4-formylbenzenesulfonate dehydrogenase
EC 1.2.1.63 6-oxohexanoate dehydrogenase
EC 1.2.1.64 4-hydroxybenzaldehyde dehydrogenase (NAD+)
EC 1.2.1.65 salicylaldehyde dehydrogenase
EC 1.2.1.66 transferred now EC 1.1.1.306
EC 1.2.1.67 vanillin dehydrogenase
EC 1.2.1.68 coniferyl-aldehyde dehydrogenase
EC 1.2.1.69 fluoroacetaldehyde dehydrogenase
EC 1.2.1.70 glutamyl-tRNA reductase
EC 1.2.1.71 succinylglutamate-semialdehyde dehydrogenase
EC 1.2.1.72 erythrose-4-phosphate dehydrogenase
EC 1.2.1.73 sulfoacetaldehyde dehydrogenase
EC 1.2.1.74 abieta-7,13-dien-18-al dehydrogenase
EC 1.2.1.75 malonyl CoA reductase (malonate semialdehyde-forming)
EC 1.2.1.76 succinate-semialdehyde dehydrogenase (acetylating)
EC 1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
EC 1.2.1.78 2-formylbenzoate dehydrogenase
EC 1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
EC 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
EC 1.2.1.81 sulfoacetaldehyde dehydrogenase (acylating)
EC 1.2.1.82 β-apo-4'-carotenal oxygenase
EC 1.2.1.83 3-succinoylsemialdehyde-pyridine dehydrogenase
EC 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
EC 1.2.1.85 2-hydroxymuconate-6-semialdehyde dehydrogenase
EC 1.2.1.86 geranial dehydrogenase
EC 1.2.1.87 propanal dehydrogenase (CoA-propanoylating)
EC 1.2.1.88 L-glutamate γ-semialdehyde dehydrogenase
EC 1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+)
EC 1.2.1.90 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]
EC 1.2.1.91 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase
EC 1.2.1.92 3,6-anhydro-α-L-galactose dehydrogenase
EC 1.2.1.93 formate dehydrogenase (NAD+, ferredoxin)
EC 1.2.1.94 farnesal dehydrogenase
EC 1.2.1.95 L-2-aminoadipate reductase
EC 1.2.1.96 4-hydroxybenzaldehyde dehydrogenase (NADP+)
EC 1.2.1.97 3-sulfolactaldehyde dehydrogenase
EC 1.2.1.98 2-hydroxy-2-methylpropanal dehydrogenase
EC 1.2.2 With a cytochrome as acceptor
EC 1.2.2.1 formate dehydrogenase (cytochrome)
EC 1.2.2.2 deleted covered by EC 1.2.5.1
EC 1.2.2.3 formate dehydrogenase (cytochrome-c-553)
EC 1.2.2.4 carbon-monoxide dehydrogenase (cytochrome-b-561)

EC 1.2.3 With oxygen as acceptor

EC 1.2.3.1 aldehyde oxidase
EC 1.2.3.2 now EC 1.1.3.22
EC 1.2.3.3 pyruvate oxidase
EC 1.2.3.4 oxalate oxidase
EC 1.2.3.5 glyoxylate oxidase
EC 1.2.3.6 pyruvate oxidase (CoA-acetylating)
EC 1.2.3.7 indole-3-acetaldehyde oxidase
EC 1.2.3.8 pyridoxal oxidase
EC 1.2.3.9 aryl-aldehyde oxidase
EC 1.2.3.10 deleted
EC 1.2.3.11 retinal oxidase
EC 1.2.3.12 now EC 1.14.13.82
EC 1.2.3.13 4-hydroxyphenylpyruvate oxidase
EC 1.2.3.14 abscisic aldehyde oxidase
EC 1.2.3.15 (methyl)glyoxal oxidase
EC 1.2.4 With a disulfide as acceptor
EC 1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EC 1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
EC 1.2.4.3 deleted, included in EC 1.2.4.4
EC 1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
EC 1.2.5 With a quinone or similar compound as acceptor
EC 1.2.5.1 pyruvate dehydrogenase (quinone)
EC 1.2.5.2 aldehyde dehydrogenase (quinone)
EC 1.2.5.3 aerobic carbon monoxide dehydrogenase
EC 1.2.7 With an iron-sulfur protein as acceptor
EC 1.2.7.1 pyruvate synthase
EC 1.2.7.2 deleted now covered by EC 1.2.7.1
EC 1.2.7.3 2-oxoglutarate synthase
EC 1.2.7.4 anaerobic carbon-monoxide dehydrogenase
EC 1.2.7.5 aldehyde ferredoxin oxidoreductase
EC 1.2.7.6 glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)
EC 1.2.7.7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
EC 1.2.7.8 indolepyruvate ferredoxin oxidoreductase
EC 1.2.7.9 deleted, identical to EC 1.2.7.3
EC 1.2.7.10 oxalate oxidoreductase
EC 1.2.7.11 2-oxoacid oxidoreductase (ferredoxin)
EC 1.2.98 With other, known, physiological acceptors
EC 1.2.98.1 formaldehyde dismutase
EC 1.2.99.2 transferred now EC 1.2.7.4
EC 1.2.99 With unknown physiological acceptors
EC 1.2.99.1 now EC 1.17.99.4
EC 1.2.99.2 carbon-monoxide dehydrogenase (acceptor)
EC 1.2.99.3 transferred now EC 1.2.5.2
EC 1.2.99.4 transferred now EC 1.2.98.1
EC 1.2.99.5 formylmethanofuran dehydrogenase
EC 1.2.99.6 carboxylate reductase
EC 1.2.99.7 aldehyde dehydrogenase (FAD-independent)
EC 1.2.99.8 glyceraldehyde dehydrogenase (FAD-containing)
EC 1.2.99.9 formate dehydrogenase (coenzyme F420)
EC 1.3 Acting on the CH-CH group of donors

EC 1.3.1 With NAD+ or NADP+ as acceptor
EC 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
EC 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
EC 1.3.1.3 Δ4-3-oxosteroid 5β-reductase
EC 1.3.1.4 transferred, now EC 1.3.1.22
EC 1.3.1.5 cucurbitacin Δ23-reductase
EC 1.3.1.6 fumarate reductase (NADH)
EC 1.3.1.7 meso-tartrate dehydrogenase
EC 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
EC 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
EC 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
EC 1.3.1.11 2-coumarate reductase
EC 1.2.3.11 deleted now included with EC 1.2.3.1
EC 1.3.1.12 prephenate dehydrogenase
EC 1.3.1.13 prephenate dehydrogenase (NADP+)
EC 1.3.1.14 dihydroorotate dehydrogenase (NAD+)
EC 1.3.1.15 dihydroorotate dehydrogenase (NADP+)
EC 1.3.1.16 β-nitroacrylate reductase
EC 1.3.1.17 3-methyleneoxindole reductase
EC 1.3.1.18 kynurenate-7,8-dihydrodiol dehydrogenase
EC 1.3.1.19 cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
EC 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
EC 1.3.1.21 7-dehydrocholesterol reductase
EC 1.3.1.22 3-oxo-5α-steroid 4-dehydrogenase (NADP+)
EC 1.3.1.23 deleted now EC 1.3.1.3
EC 1.3.1.24 biliverdin reductase
EC 1.3.1.25 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
EC 1.3.1.26 transferred now EC 1.17.1.8
EC 1.3.1.27 2-hexadecenal reductase
EC 1.3.1.28 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
EC 1.3.1.29 cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
EC 1.3.1.30 progesterone 5α-reductase
EC 1.3.1.30 transferred, now EC 1.3.1.22
EC 1.3.1.31 2-enoate reductase
EC 1.3.1.32 maleylacetate reductase
EC 1.3.1.33 protochlorophyllide reductase
EC 1.3.1.34 2,4-dienoyl-CoA reductase (NADPH)
EC 1.3.1.35 transferred now EC 1.14.19.22
EC 1.3.1.36 geissoschizine dehydrogenase
EC 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
EC 1.3.1.40 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
EC 1.3.1.41 xanthommatin reductase
EC 1.3.1.42 12-oxophytodienoate reductase
EC 1.3.1.43 arogenate dehydrogenase
EC 1.3.1.44 trans-2-enoyl-CoA reductase (NAD+)
EC 1.3.1.45 2'-hydroxyisoflavone reductase
EC 1.3.1.46 biochanin-A reductase
EC 1.3.1.47 α-santonin 1,2-reductase
EC 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
EC 1.3.1.49 cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
EC 1.3.1.50 now EC 1.1.1.252
EC 1.3.1.51 2'-hydroxydaidzein reductase
EC 1.3.1.52 transferred now EC 1.3.8.5
EC 1.3.1.53 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
EC 1.3.1.54 precorrin-6A reductase
EC 1.3.1.55 now EC 1.3.1.25
EC 1.3.1.56 cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
EC 1.3.1.57 phloroglucinol reductase
EC 1.3.1.58 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
EC 1.3.1.59 deleted entry.
EC 1.3.1.60 dibenzothiophene dihydrodiol dehydrogenase
EC 1.3.1.61 deleted, identical to EC 1.3.1.53
EC 1.3.1.62 pimeloyl-CoA dehydrogenase
EC 1.3.1.63 transferred now EC 1.21.1.2
EC 1.3.1.64 phthalate 4,5-cis-dihydrodiol dehydrogenase
EC 1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase
EC 1.3.1.66 cis-dihydroethylcatechol dehydrogenase
EC 1.3.1.67 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
EC 1.3.1.68 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase
EC 1.3.1.69 zeatin reductase
EC 1.3.1.70 Δ14-sterol reductase
EC 1.3.1.71 Δ24(241)-sterol reductase
EC 1.3.1.72 Δ24-sterol reductase
EC 1.3.1.73 1,2-dihydrovomilenine reductase
EC 1.3.1.74 2-alkenal reductase [NAD(P)+]
EC 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
EC 1.3.1.76 precorrin-2 dehydrogenase
EC 1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
EC 1.3.1.78 arogenate dehydrogenase (NADP+)
EC 1.3.1.79 arogenate dehydrogenase [NAD(P)+]
EC 1.3.1.80 transferred now EC 1.3.7.12
EC 1.3.1.81 (+)-pulegone reductase
EC 1.3.1.82 (–)-isopiperitenone reductase
EC 1.3.1.83 geranylgeranyl diphosphate reductase
EC 1.3.1.84 acrylyl-CoA reductase (NADPH)
EC 1.3.1.85 crotonyl-CoA carboxylase/reductase
EC 1.3.1.86 crotonyl-CoA reductase
EC 1.3.1.87 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase
EC 1.3.1.88 tRNA-dihydrouridine16/17 synthase [NAD(P)+]
EC 1.3.1.89 tRNA-dihydrouridine47 synthase [NAD(P)+]
EC 1.3.1.90 tRNA-dihydrouridine20a/20b synthase [NAD(P)+]
EC 1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+]
EC 1.3.1.92 artemisinic aldehyde Δ11(13)-reductase
EC 1.3.1.93 very-long-chain enoyl-CoA reductase
EC 1.3.1.94 polyprenol reductase
EC 1.3.1.95 acrylyl-CoA reductase (NADH)
EC 1.3.1.96 Botryococcus squalene synthase
EC 1.3.1.97 botryococcene synthase
EC 1.3.1.98 UDP-N-acetylmuramate dehydrogenase
EC 1.3.1.99 iridoid synthase
EC 1.3.1.100 chanoclavine-I aldehyde reductase
EC 1.3.1.101 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]
EC 1.3.1.102 2-alkenal reductase (NADP+)
EC 1.3.1.103 2-haloacrylate reductase
EC 1.3.1.104 enoyl-[acyl-carrier-protein] reductase
EC 1.3.1.105 2-methylene-furan-3-one reductase
EC 1.3.1.106 cobalt-precorrin-6A reductase
EC 1.3.1.107 sanguinarine reductase
EC 1.3.1.108 caffeoyl-CoA reductase
EC 1.3.1.109 butanoyl-CoA dehydrogenase (NAD+, ferredoxin)
EC 1.3.1.110 lactate dehydrogenase (NAD+, ferredoxin)
EC 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase
EC 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
EC 1.3.2 With a cytochrome as acceptor
EC 1.3.2.1 now EC 1.3.99.2
EC 1.3.2.2 now EC 1.3.99.3
EC 1.3.2.3 L-galactonolactone dehydrogenase
EC 1.3.3 With oxygen as acceptor
EC 1.3.3.1 transferred now EC 1.3.98.1
EC 1.3.3.2 now EC 1.14.21.6
EC 1.3.3.3 coproporphyrinogen oxidase
EC 1.3.3.4 protoporphyrinogen oxidase
EC 1.3.3.5 bilirubin oxidase
EC 1.3.3.6 acyl-CoA oxidase
EC 1.3.3.7 dihydrouracil oxidase
EC 1.3.3.8 tetrahydroberberine oxidase
EC 1.3.3.9 secologanin synthase
EC 1.3.3.10 tryptophan α,β-oxidase
EC 1.3.3.11 pyrroloquinoline-quinone synthase
EC 1.3.3.12 L-galactonolactone oxidase
EC 1.3.3.13 albonoursin synthase
EC 1.3.3.14 aclacinomycin-A oxidase
EC 1.3.3.15 coproporphyrinogen III oxidase (coproporphyrin-forming)
EC 1.3.4 With a disulfide as acceptor
EC 1.3.4.1 fumarate reductase (CoM/CoB)
EC 1.3.5 With a quinone or related compound as acceptor
EC 1.3.5.1 succinate dehydrogenase (quinone)
EC 1.3.5.2 dihydroorotate dehydrogenase (quinone)
EC 1.3.5.3 protoporphyrinogen IX dehydrogenase (menaquinone)
EC 1.3.5.4 fumarate reductase (quinol)
EC 1.3.5.5 15-cis-phytoene desaturase
EC 1.3.5.6 9,9'-dicis-ζ-carotene desaturase
EC 1.3.7 With an iron-sulfur protein as acceptor
EC 1.3.7.1 6-hydroxynicotinate reductase
EC 1.3.7.2 15,16-dihydrobiliverdin:ferredoxin oxidoreductase
EC 1.3.7.3 phycoerythrobilin:ferredoxin oxidoreductase
EC 1.3.7.4 phytochromobilin:ferredoxin oxidoreductase
EC 1.3.7.5 phycocyanobilin:ferredoxin oxidoreductase
EC 1.3.7.6 phycoerythrobilin synthase
EC 1.3.7.7 ferredoxin:protochlorophyllide reductase (ATP-dependent)
EC 1.3.7.8 benzoyl-CoA reductase
EC 1.3.7.9 4-hydroxybenzoyl-CoA reductase
EC 1.3.7.10 transferred now EC 1.14.19.8
EC 1.3.7.11 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase
EC 1.3.7.12 red chlorophyll catabolite reductase
EC 1.3.7.13 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin)
EC 1.3.7.14 3,8-divinyl chlorophyllide a reductase
EC 1.3.7.15 chlorophyllide a reductase
EC 1.3.8 With flavin as acceptor
EC 1.3.8.1 short-chain acyl-CoA dehydrogenase
EC 1.3.8.2 4,4'-diapophytoene desaturase
EC 1.3.8.3 (R)-benzylsuccinyl-CoA dehydrogenase
EC 1.3.8.4 isovaleryl-CoA dehydrogenase
EC 1.3.8.5 2-methyl-branched-chain-enoyl-CoA reductase
EC 1.3.8.6 glutaryl-CoA dehydrogenase (decarboxylating)
EC 1.3.8.7 medium-chain acyl-CoA dehydrogenase
EC 1.3.8.8 long-chain acyl-CoA dehydrogenase
EC 1.3.8.9 very-long-chain acyl-CoA dehydrogenase
EC 1.3.8.10 cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
EC 1.3.8.11 cyclohexane-1-carbonyl-CoA dehydrogenase
EC 1.3.8.12 (2S)-methylsuccinyl-CoA dehydrogenase
EC 1.3.8.13 crotonobetainyl-CoA reductase
EC 1.3.98 With other, known, physiological acceptors
EC 1.3.98.1 dihydroorotate dehydrogenase (fumarate)
EC 1.3.98.2 transferred now EC 1.3.4.1
EC 1.3.98.3 coproporphyrinogen dehydrogenase
EC 1.3.98.4 5a,11a-dehydrotetracycline reductase
EC 1.3.99 With unknown physiological acceptors

EC 1.3.99.1 deleted, included with EC 1.3.5.1
EC 1.3.99.2 transferred now EC 1.3.8.1
EC 1.3.99.3 transferred now EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9
EC 1.3.99.4 3-oxosteroid 1-dehydrogenase
EC 1.3.99.5 3-oxo-5α-steroid 4-dehydrogenase (acceptor)
EC 1.3.99.6 3-oxo-5β-steroid 4-dehydrogenase
EC 1.3.99.7 transferred now EC 1.3.8.6
EC 1.3.99.8 2-furoyl-CoA dehydrogenase
EC 1.3.99.9 now EC 1.21.99.1
EC 1.3.99.10 transferred now EC 1.3.8.4
EC 1.3.99.11 now EC 1.3.5.2
EC 1.3.99.11 dihydroorotate dehydrogenase
EC 1.3.99.12 2-methylacyl-CoA dehydrogenase
EC 1.3.99.13 transferred now EC 1.3.8.8
EC 1.3.99.14 cyclohexanone dehydrogenase
EC 1.3.99.15 transferred now EC 1.3.7.8
EC 1.3.99.16 isoquinoline 1-oxidoreductase
EC 1.3.99.17 quinoline 2-oxidoreductase
EC 1.3.99.18 quinaldate 4-oxidoreductase
EC 1.3.99.19 quinoline-4-carboxylate 2-oxidoreductase
EC 1.3.99.20 transferred now EC 1.3.7.9
EC 1.3.99.21 transferred now EC 1.3.8.3
EC 1.3.99.22 transferred, now EC 1.3.98.3
EC 1.3.99.23 all-trans-retinol 13,14-reductase
EC 1.3.99.24 2-amino-4-deoxychorismate dehydrogenase
EC 1.3.99.25 carvone reductase
EC 1.3.99.26 all-trans-ζ-carotene desaturase
EC 1.3.99.27 1-hydroxycarotenoid 3,4-desaturase
EC 1.3.99.28 phytoene desaturase (neurosporene-forming)
EC 1.3.99.29 phytoene desaturase (ζ-carotene-forming)
EC 1.3.99.30 phytoene desaturase (3,4-didehydrolycopene-forming)
EC 1.3.99.31 phytoene desaturase (lycopene-forming)
EC 1.3.99.32 glutaryl-CoA dehydrogenase (non-decarboxylating)
EC 1.3.99.33 urocanate reductase
EC 1.3.99.34 transferred now EC 1.3.7.11
EC 1.3.99.35 transferred, now EC 1.3.7.15
EC 1.3.99.36 cypemycin cysteine dehydrogenase (decarboxylating)
EC 1.3.99.37 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase
EC 1.3.99.38 menaquinone-9 β-reductase

Continued with contents EC 1.4 to EC 1.97
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