IUBMB Enzyme Nomenclature


Accepted name: (S)-scoulerine 9-O-methyltransferase

Reaction: S-adenosyl-L-methionine + (S)-scoulerine = S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine

For diagram click here.

Systematic name: S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase

Comments: the product of this reaction is a precursor for protoberberine alkaloids in plants

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 96380-65-3


1. Muemmler, S., Rueffer, M., Nagakura, N., Zenk, M.H. S-Adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase, a highly stereo- and regiospecific enzyme in tetrahydroberberine biosynthesis. Plant Cell Reports 4 (1985) 36-39.

[EC created 1999]

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