IUBMB Enzyme Nomenclature


Accepted name: 16S rRNA (uracil1498-N3)-methyltransferase

Reaction: S-adenosyl-L-methionine + uracil1498 in 16S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil1498 in 16S rRNA

Other name(s): DUF558 protein; YggJ; RsmE; m3U1498 specific methyltransferase

Systematic name: S-adenosyl-L-methionine:16S rRNA (uracil1498-N3)-methyltransferase

Comments: The enzyme specifically methylates uracil1498 at N3 in 16S rRNA.

Links to other databases: BRENDA, EXPASY, KEGG, PDB, Metacyc, CAS registry number:


1. Basturea, G.N., Rudd, K.E. and Deutscher, M.P. Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family. RNA 12 (2006) 426-434. [PMID: 16431987]

2. Basturea, G.N. and Deutscher, M.P. Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE. RNA 13 (2007) 1969-1976. [PMID: 17872509]

[EC created 2010]

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