IUBMB Enzyme Nomenclature

EC 2.1.1.62

Accepted name: mRNA (2'-O-methyladenosine-N6-)-methyltransferase

Reaction: S-adenosyl-L-methionine + m7G(5')pppAm = S-adenosyl-L-homocysteine + m7G(5')pppm6Am (mRNA containing an N6,2'-O-dimethyladenosine cap)

Other name(s): messenger ribonucleate 2'-O-methyladenosine NG-methyltransferase

Systematic name: S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 68009-87-0

References:

1. Keith, J.M., Ensinger, M.J. and Moss, B. HeLa cell RNA (2'-O-methyladenosine-N6-)-methyltransferase specific for the capped 5'-end of messenger RNA. J. Biol. Chem. 253 (1978) 5033-5039. [PMID: 670176]

[EC 2.1.1.62 created 1982]


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