Reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone
For diagram click here.
Other name(s): flavonoid O-methyltransferase; flavonoid methyltransferase
Systematic name: S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase
Comments: Converts apigenin into acacetin. Naringenin (5,7,4'-trihydroxy-flavanone) can also act as an acceptor, but more slowly.
Links to other databases: BRENDA, EXPASY, KEGG, ERGO, CAS registry number: 118251-36-8
References:
1. Kuroki, G. and Poulton, J.E. The para-O-methylation of apigenin to acacetin by cell-free extracts of Robinia pseudoacacia L. Z. Naturforsch. C: Biosci. 36 (1981) 916-920.