Reaction: S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
Other name(s): 3-hydroxyanthranilate 4-methyltransferase
Systematic name: S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase
Comments: Involved in the biosynthesis of the antibiotic actinomycin in Streptomyces antibioticus.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 112445-22-4
1. Fawaz, F. and Jones, G.H. Actinomycin synthesis in Streptomyces antibioticus. Purification and properties of a 3-hydroxyanthranilate 4-methyltransferase. J. Biol. Chem. 263 (1988) 4602-4606. [PMID: 2450873]