IUBMB Enzyme Nomenclature


Accepted name: 3-hydroxyanthranilate 4-C-methyltransferase

Reaction: S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate

Other name(s): 3-hydroxyanthranilate 4-methyltransferase

Systematic name: S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase

Comments: Involved in the biosynthesis of the antibiotic actinomycin in Streptomyces antibioticus.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 112445-22-4


1. Fawaz, F. and Jones, G.H. Actinomycin synthesis in Streptomyces antibioticus. Purification and properties of a 3-hydroxyanthranilate 4-methyltransferase. J. Biol. Chem. 263 (1988) 4602-4606. [PMID: 2450873]

[EC created 1990]

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