IUBMB Enzyme Nomenclature


Accepted name: D-alanine 2-hydroxymethyltransferase

Reaction: 5,10-methylenetetrahydrofolate + D-alanine + H2O = tetrahydrofolate + 2-methylserine

Other name(s): 2-methylserine hydroxymethyltransferase

Systematic name: 5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase

Comments: Also acts on 2-hydroxymethylserine.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 9075-76-7


1. Wilson, E.M. and Snell, E.E. Metabolism of α-methylserine. I. α-Methylserine hydroxymethyltransferase. J. Biol. Chem. 237 (1962) 3171-3179.

[EC created 1972]

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