IUBMB Enzyme Nomenclature


Accepted name: deoxycytidylate 5-hydroxymethyltransferase

Reaction: 5,10-methylenetetrahydrofolate + H2O + deoxycytidylate = tetrahydrofolate + 5-hydroxymethyldeoxycytidylate

Other name(s): dCMP hydroxymethylase; d-cytidine 5'-monophosphate hydroxymethylase; deoxyCMP hydroxymethylase; deoxycytidylate hydroxymethylase; deoxycytidylic hydroxymethylase

Systematic name: 5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9012-68-4


1. Mathews, C.K., Brown, F. and Cohen, S.S. Virus-induced acquisition of metabolic function. VII. Biosynthesis de novo of deoxycytidylate hydroxymethylase. J. Biol. Chem. 239 (1964) 2957-2963.

[EC created 1972]

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