IUBMB Enzyme Nomenclature


Accepted name: putrescine carbamoyltransferase

Reaction: carbamoyl phosphate + putrescine = phosphate + N-carbamoylputrescine

Other name(s): PTCase; putrescine synthase; putrescine transcarbamylase

Systematic name: carbamoyl-phosphate:putrescine carbamoyltransferase

Comments: The plant enzyme also catalyses the reactions of EC ornithine carbamoyltransferase, EC carbamate kinase and EC agmatine deiminase, thus acting as putrescine synthase, converting agmatine [(4-aminobutyl)guanidine] and ornithine into putrescine and citrulline, respectively.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9076-55-5


1. Roon, R.J. and Barker, H.A. Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase. J. Bacteriol. 109 (1972) 44-50. [PMID: 4621632]

2. Srivenugopal, K.S. and Adiga, P.R. Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase). J. Biol. Chem. 256 (1981) 9532-9541. [PMID: 6895223]

[EC created 1976]

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