IUBMB Enzyme Nomenclature

EC 2.3.1.108

Accepted name: α-tubulin N-acetyltransferase

Reaction: acetyl-CoA + [α-tubulin]-L-lysine = CoA + [α-tubulin]-N6-acetyl-L-lysine

Other name(s): α-tubulin acetylase; TAT; α-tubulin acetyltransferase; tubulin N-acetyltransferase; acetyl-CoA:α-tubulin-L-lysine Nε-acetyltransferase

Systematic name: acetyl-CoA:[α-tubulin]-L-lysine N6-acetyltransferase

Comments: The enzyme from Chlamydomonas flagella also acetylates mammalian brain α-tubulin.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 99889-90-4

References:

1. Greer, K., Maruta, H., L'Hernault, S.W. and Rosenbaum, J.L. α-Tubulin acetylase activity in isolated Chlamydomonas flagella. J. Cell Biol. 101 (1985) 2081-2084. [PMID: 4066751]

[EC 2.3.1.108 created 1989]


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