IUBMB Enzyme Nomenclature


Accepted name: isoflavone-7-O-β-glucoside 6"-O-malonyltransferase

Reaction: malonyl-CoA + biochanin A 7-O-β-D-glucoside = CoA + biochanin A 7-O-(6-O-malonyl-β-D-glucoside)

See diagram for reaction with 7-O-β-D-glucosides of biochanin A or apigenin.

Other name(s): flavone/flavonol 7-O-β-D-glucoside malonyltransferase; flavone (flavonol) 7-O-glycoside malonyltransferase; malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase; MAT-7; malonyl-coenzyme A:isoflavone 7-O-glucoside-6"-malonyltransferase; malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase

Systematic name: malonyl-CoA:isoflavone-7-O-β-D-glucoside 6"-O-malonyltransferase

Comments: The 6-position of the glucose residue of formononetin can also act as acceptor; some other 7-O-glucosides of isoflavones, flavones and flavonols can also act, but more slowly.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 93585-97-8 and 78413-09-9


1. Koester, J., Bussmann, R. and Barz, W. Malonyl-coenzyme A:isoflavone 7-O-glucoside-6"-O-malonyltransferase from roots of chick pea (Cicer arietinum L.). Arch. Biochem. Biophys. 234 (1984) 513-521. [PMID: 6497385]

2. Matern, U., Feser, C. and Hammer, D. Further characterization and regulation of malonyl-coenzyme A: flavonoid glucoside malonyltransferases from parsley cell suspension cultures. Arch. Biochem. Biophys. 226 (1983) 206-217. [PMID: 6639051]

[EC created 1989]

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