Reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine
Other name(s): arylhydroxamate N,O-acetyltransferase; arylamine N-acetyltransferase; N-hydroxy-2-aminofluorene-O-acetyltransferase
Systematic name: acetyl-CoA:N-hydroxyarylamine O-acetyltransferase
Comments: The enzyme from liver, but not that from bacteria, can also catalyse N-acetylation of arylamines and N,O-acetylation of arylhydroxamates.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 100984-92-7
1. Saito, K., Shinohara, A. and Kamataki, T. N-Hydroxyarylamine O-acetyltransferase in hamster liver: identity with arylhydroxamic acid N,O-acetyltransferase and arylamine N-acetyltransferase. J. Biochem. (Tokyo) 99 (1986) 1689-1697. [PMID: 3745141]