IUBMB Enzyme Nomenclature


Accepted name: glycine N-acyltransferase

Reaction: acyl-CoA + glycine = CoA + N-acylglycine

Other name(s): glycine acyltransferase; glycine-N-acylase

Systematic name: acyl-CoA:glycine N-acyltransferase

Comments: The CoA derivatives of a number of aliphatic and aromatic acids, but not phenylacetyl-CoA or (indol-3-yl)acetyl-CoA, can act as donor. Not identical with EC glutamine N-acyltransferase or EC glycine N-benzoyltransferase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9029-95-2


1. Nandi, D.L., Lucas, S.V. and Webster, L.T. Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization. J. Biol. Chem. 254 (1979) 7230-7237. [PMID: 457678]

2. Schachter, D. and Taggart, J.V. Glycine N-acylase: purification and properties. J. Biol. Chem. 208 (1954) 263-275. [PMID: 13174534]

3. Webster, L.T., Jr., Siddiqui, U.A., Lucas, S.V., Strong, J.M. and Mieyal, J.J. Identification of N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man. J. Biol. Chem. 251 (1976) 3352-3358. [PMID: 931988]

[EC created 1961]

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