Reaction: acetyl-CoA + α-D-glucosamine 1-phosphate = CoA + N-acetyl-α-D-glucosamine 1-phosphate
For diagram click here.
Other Name(s): acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase
Systematic name: acetyl-CoA:α-D-glucosamine-1-phosphate N-acetyltransferase
Comments: The enzyme from several bacteria (e.g., Escherichia coli, Bacillus subtilis and Haemophilus influenzae) has been shown to be bifunctional and also to possess the activity of EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase.
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 9031-91-8
References:
1. Mengin-Lecreulx, D. and van Heijenoort, J. Copurification of glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase activities of Escherichia coli: characterization of the glmU gene product as a bifunctional enzyme catalyzing two subsequent steps in the pathway for UDP-N-acetylglucosamine synthesis. J. Bacteriol. 176: (1994) 5788-5795. [PMID: 8083170]