IUBMB Enzyme Nomenclature


Accepted name: dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase

Reaction: acetyl-CoA + dTDP-4-amino-4,6-dideoxy-α-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-α-D-galactose

For diagram of reaction click here.

Glossary: dTDP-4-amino-4,6-dideoxy-α-D-galactose = dTDP-α-D-fucosamine

Other name(s): TDP-fucosamine acetyltransferase; WecD; RffC

Systematic name: acetyl-CoA:dTDP-4-amino-4,6-dideoxy-α-D-galactose N-acetyltransferase

Comments: The product, TDP-4-acetamido-4,6-dideoxy-D-galactose, is utilized in the biosynthesis of enterobacterial common antigen (ECA).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Hung, M.N., Rangarajan, E., Munger, C., Nadeau, G., Sulea, T. and Matte, A. Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis. J. Bacteriol. 188 (2006) 5606-5617. [PMID: 16855251]

[EC created 2012]

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