IUBMB Enzyme Nomenclature


Accepted name: 2-acylglycerol O-acyltransferase

Reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol

Other name(s): acylglycerol palmitoyltransferase; monoglyceride acyltransferase; acyl coenzyme A-monoglyceride acyltransferase; monoacylglycerol acyltransferase

Systematic name: acyl-CoA:2-acylglycerol O-acyltransferase

Comments: Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. The sn-1 position and the sn-3 position are both acylated, at about the same rate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9055-17-8


1. Manganaro, F. and Kuksis, A. Purification and preliminary characterization of 2-monoacylglycerol acyltransferase from rat intestinal villus cells. Can. J. Biochem. Cell Biol. 63 (1985) 341-347. [PMID: 4016575]

[EC created 1972, modified 1986, modified 1989]

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