IUBMB Enzyme Nomenclature


Accepted name: glycerone-phosphate O-acyltransferase

Reaction: acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate

Other name(s): dihydroxyacetone phosphate acyltransferase

Systematic name: acyl-CoA:glycerone-phosphate O-acyltransferase

Comments: A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37257-19-5


1. Ballas, L.M. and Bell, R.M. Topography of glycerolipid synthetic enzymes. Synthesis of phosphatidylserine, phosphatidylinositol and glycerolipid intermediates occurs on the cytoplasmic surface of rat liver microsomal vesicles. Biochim. Biophys. Acta 665 (1981) 586-595. [PMID: 6271231]

2. Declercq, P.E., Haagsman, H.P., Van Veldhoven, P., Debeer, L.J., Van Golde, L.M.G. and Mannaerts, G.P. Rat liver dihydroxyacetone-phosphate acyltransferases and their contribution to glycerolipid synthesis. J. Biol. Chem. 259 (1984) 9064-9075.

3. Hajra, A.K. Biosynthesis of acyl dihydroxyacetone phosphate in guinea pig liver mitochondria. J. Biol. Chem. 243 (1968) 3458-3465. [PMID: 5656381]

[EC created 1972]

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