IUBMB Enzyme Nomenclature

EC 2.3.1.48

Accepted name: histone acetyltransferase

Reaction: acetyl-CoA + histone = CoA + acetylhistone

Other name(s): nucleosome-histone acetyltransferase; histone acetokinase; histone acetylase; histone transacetylase

Systematic name: acetyl-CoA:histone acetyltransferase

Comments: A group of enzymes with differing specificities towards histone acceptors.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9054-51-7

References:

1. Gallwitz, D. and Sures, I. Histone acetylation. Purification and properties of three histone-specific acetyltransferases from rat thymus nuclei. Biochim. Biophys. Acta 263 (1972) 315-328. [PMID: 5031160]

[EC 2.3.1.48 created 1976]


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