IUBMB Enzyme Nomenclature


Accepted name: diamine N-acetyltransferase

Reaction: acetyl-CoA + an alkane-α,ω-diamine = CoA + an N-acetyldiamine

Glossary: spermidine

Other name(s): spermidine acetyltransferase; putrescine acetyltransferase; putrescine (diamine)-acetylating enzyme; diamine acetyltransferase; spermidine/spermine N1-acetyltransferase; spermidine N1-acetyltransferase; acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase; putrescine acetylase; putrescine N-acetyltransferase

Systematic name: acetyl-CoA:alkane-α,ω-diamine N-acetyltransferase

Comments: Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N1- and N8-acetylspermidine), spermine, N1-acetylspermidine and N8-acetylspermidine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 54596-36-0


1. Della Ragione, F. and Pegg, A.E. Purification and characterization of spermidine/spermine N1-acetyltransferase from rat liver. Biochemistry 21 (1982) 6152-6158. [PMID: 7150547]

[EC created 1976, modified 1989]

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