IUBMB Enzyme Nomenclature


Accepted name: diacylglycerol—sterol O-acyltransferase

Reaction: 1,2-diacyl-sn-glycerol + sterol = a 1-acyl-sn-glycerol + sterol ester

Other name(s): 1,2-diacyl-sn-glycerol:sterol acyl transferase

Systematic name: 1,2-diacyl-sn-glycerol:sterol O-acyltransferase

Comments: Cholesterol, sitosterol, campesterol and diacylglycerol can act as acceptors. Transfers a number of long-chain fatty acyl groups.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 79586-23-5


1. Bartlett, K., Keat, M.J. and Mercer, E.I. Biosynthesis of sterol esters in Phycomyces blakesleeanus. Phytochemistry 13 (1974) 1107-1113.

2. Garcia, R.E. and Mudd, J.B. Metabolism of monoacylglycerol and diacylglycerol by enzyme preparations from spinach leaves. Arch. Biochem. Biophys. 191 (1978) 487-493. [PMID: 742884]

3. Garcia, R.E. and Mudd, J.B. 1,2-Diacyl-sn-glycerol:sterol acyl transferase from spinach leaves (Spinacia oleracea L.). Methods Enzymol. 71 (1981) 768-772.

[EC created 1984]

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