IUBMB Enzyme Nomenclature

EC 2.4.1.142

Accepted name: chitobiosyldiphosphodolichol β-mannosyltransferase

Reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + β-(1→4)-D-mannosylchitobiosyldiphosphodolichol

For diagram of reaction click here.

Other name(s): guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase

Systematic name: GDP-mannose:chitobiosyldiphosphodolichol β-D-mannosyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 83380-85-2

References:

1. Sharma, C.B., Lehle, L. and Tanner, W. Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast. Eur. J. Biochem. 126 (1982) 319-325. [PMID: 6215245]

2. Takahashi, T., Honda, R. and Nishikawa, Y. Cloning of the human cDNA which can complement the defect of the yeast mannosyltransferase I-deficient mutant alg 1. Glycobiology 10 (2000) 321-327. [PMID: 10704531]

[EC 2.4.1.142 created 1984, modified 2001]


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