Reaction: UDP-N-acetyl-D-glucosamine + β-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R
Other name(s): uridine diphosphoacetylglucosamine-acetyllactosaminide β1![[arrow right]](../../../../greek/ARROWR.GIF)
3-acetylglucosaminyltransferase; poly-N-acetyllactosamine extension enzyme; Galβ14GlcNAc-R β13 N-acetylglucosaminyltransferase; UDP-GlcNAc:GalR, β-D-3-N-acetylglucosaminyltransferase; N-acetyllactosamine β(1-3)N-acetylglucosaminyltransferase; UDP-GlcNAc:Galβ14GlcNAcβ-Rβ13-N-acetylglucosaminyltransferase
Systematic name: UDP-N-acetyl-D-glucosamine:β-D-galactosyl-1,4-N-acetyl-D-glucosamine β-1,3-acetyl-D-glucosaminyltransferase
Comments: Acts on β-galactosyl-1,4-N-acetylglucosaminyl termini on asialo-α1-acid glycoprotein and other glycoproteins and oligosaccharides.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 85638-39-7
References:
1. Takeya, A., Hosomi, O. and Kogure, T. The presence of N-acetyllactosamine and lactose: β (1-3)N-acetylglucosaminyltransferase activity in human urine. Jpn. J. Med. Sci. Biol. 38 (1985) 1-8. [PMID: 3160874
2. Van den Eijnden, D.H., Winterwerp, H., Smeeman, P. and Schiphorst, W.E.C.M. Novikoff ascites tumor cells contain N-acetyllactosaminide β13 and β16 N-acetylglucosaminyltransferase activity. J. Biol. Chem. 258 (1983) 3435-3437. [PMID: 6219989]