IUBMB Enzyme Nomenclature

EC 2.4.1.150

Accepted name: N-acetyllactosaminide β-1,6-N-acetylglucosaminyl-transferase

Reaction: UDP-N-acetyl-D-glucosamine + β-D-galactosyl-(1→4)-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-β-D-glucosaminyl-(1→6)-β-D-galactosyl-(1→4)-N-acetyl-D-glucosaminyl-R

Other name(s): N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine-acetyllactosaminide β1→6-acetylglucosaminyltransferase; Galβ1→4GlcNAc-R β1→6 N-acetylglucosaminyltransferase; UDP-GlcNAc:Gal-R, β-D-6-N-acetylglucosaminyltransferase

Systematic name: UDP-N-acetyl-D-glucosamine:β-D-galactosyl-(1→4)-N-acetyl-D-glucosaminide β-1,6-N-acetyl-D-glucosaminyltransferase

Comments: Acts on β-galactosyl-(1→4)-N-acetylglucosaminyl termini on asialo-α1-acid glycoprotein.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 85638-40-0

References:

1. Van den Eijnden, D.H., Winterwerp, H., Smeeman, P. and Schiphorst, W.E.C.M. Novikoff ascites tumor cells contain N-acetyllactosaminide β1[arrow right]3 and β1[arrow right]6 N-acetylglucosaminyltransferase activity. J. Biol. Chem. 258 (1983) 3435-3437. [PMID: 6219989]

[EC 2.4.1.150 created 1984]


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