IUBMB Enzyme Nomenclature

EC 2.4.1.16

Accepted name: chitin synthase

Reaction: UDP-N-acetyl-α-D-glucosamine + [4)-N-acetyl-β-D-glucosaminyl-(1→]n = UDP + [4)-N-acetyl-β-D-glucosaminyl-(1→]n+1

Other name(s): chitin-UDP N-acetylglucosaminyltransferase; chitin-uridine diphosphate acetylglucosaminyltransferase; chitin synthetase; trans-N-acetylglucosaminosylase

Systematic name: UDP-N-acetyl-D-glucosamine:chitin 4-β-N-acetylglucosaminyltransferase

Comments: Converts UDP-N-acetyl-D-glucosamine into chitin and UDP.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9030-18-6

References:

1. Glaser, L. and Brown, D.H. The synthesis of chitin in cell-free extracts of Neurospora crassa. J. Biol. Chem. 228 (1957) 729-742.

2. Sburlati, A. and Cabib, E. Chitin synthetase 2, a presumptive participant in septum formation in Saccharomyces cerevisiae. J. Biol. Chem. 261 (1986) 15147-15152. [PMID: 2945823]

[EC 2.4.1.16 created 1961]


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