Reaction: UDP-glucose + an isoflavone = UDP + an isoflavone 7-O-β-D-glucoside
See diagram for reaction on biochanin A or formononetin.
Other name(s): uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase; UDP-glucose-favonoid 7-O-glucosyltransferase; UDP-glucose:isoflavone 7-O-glucosyltransferase
Systematic name: UDP-glucose:isoflavone 7-O-β-D-glucosyltransferase
Comments: The 4'-methoxy isoflavones biochanin A and formononetin and, more slowly, the 4'-hydroxyisoflavones genistein and daidzein, can act as acceptors. The enzyme does not act on isoflavanones, flavones, flavanones, flavanols or coumarins.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 97089-62-8
1. Köster, J. and Barz, W. UDP-glucose:isoflavone 7-O-glucosyltransferase from roots of chick pea (Cicer arietinum L.). Arch. Biochem. Biophys. 212 (1981) 98-104. [PMID: 6458246]