IUBMB Enzyme Nomenclature


Accepted name: lactosylceramide β-1,3-galactosyltransferase

Reaction: UDP-α-D-galactose + β-D-galactosyl-(1→4)-β-D-glucosyl-R = UDP + β-D-galactosyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-R

For diagram of reaction click here.

Other name(s): uridine diphosphogalactose-lactosylceramide β1→3-galactosyltransferase; UDP-galactose:D-galactosyl-1,4-β-D-glucosyl-R β-1,3-galactosyltransferase

Systematic name: UDP-α-D-galactose:β-D-galactosyl-1,4-β-D-glucosyl-R β-1,3-galactosyltransferase

Comments: R may be an oligosaccharide or a glycolipid; lactose can also act as acceptor, but more slowly. Involved in the elongation of oligosaccharide chains, especially in glycolipids.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 106769-64-6


1. Bailly, P., Piller, F. and Cartron, J.-P. Characterization and specific assay for a galactoside β-3-galactosyltransferase of human kidney. Eur. J. Biochem. 173 (1988) 417-422. [PMID: 3129295]

[EC created 1989]

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