IUBMB Enzyme Nomenclature

EC 2.4.2.11

Accepted name: nicotinate phosphoribosyltransferase

Reaction: nicotinate β-D-ribonucleotide + diphosphate = nicotinate + 5-phospho-α-D-ribose 1-diphosphate

For diagram of reaction click here.

Other name(s): niacin ribonucleotidase; nicotinic acid mononucleotide glycohydrolase; nicotinic acid mononucleotide pyrophosphorylase; nicotinic acid phosphoribosyltransferase; nicotinate-nucleotide:diphosphate phospho-α-D-ribosyltransferase; nicotinate-D-ribonucleotide:diphosphate phospho-α-D-ribosyltransferase

Systematic name: nicotinate-β-D-ribonucleotide:diphosphate phospho-α-D-ribosyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9030-26-6

References:

1. Imsande, J. Pathway of diphosphopyridine nucleotide biosynthesis in Escherichia coli. J. Biol. Chem. 236 (1961) 1494-1497.

2. Imsande, J. and Handler, P. Biosynthesis of diphosphopyridine nucleotide. III. Nicotinic acid mononucleotide pyrophosphorylase. J. Biol. Chem. 236 (1961) 525-530.

3. Kosaka, A., Spivey, H.O. and Gholson, R.K. Nicotinate phosphoribosyltransferase of yeast. Purification and properties. J. Biol. Chem. 246 (1971) 3277-3283. [PMID: 4324895]

[EC 2.4.2.11 created 1961]


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