IUBMB Enzyme Nomenclature


Accepted name: dioxotetrahydropyrimidine phosphoribosyltransferase

Reaction: A 2,4-dioxotetrahydropyrimidine D-ribonucleotide + diphosphate = a 2,4-dioxotetrahydropyrimidine + 5-phospho-α-D-ribose 1-diphosphate

Other name(s): dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase; dioxotetrahydropyrimidine phosphoribosyl transferase; dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase; 2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-α-D-ribosyltransferase

Systematic name: 2,4-dioxotetrahydropyrimidine-D-ribonucleotide:diphosphate phospho-α-D-ribosyltransferase

Comments: Acts (in the reverse direction) on uracil and other pyrimidines and pteridines containing a 2,4-diketo structure.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37277-75-1


1. Hatfield, D. and Wyngaarden, J.B. 3-Ribosylpurines. I. Synthesis of (3-ribosyluric acid) 5'-phosphate and (3-ribosylxanthine) 5'-phosphate by a pyrimidine ribonucleotide pyrophosphorylase of beef erythrocytes. J. Biol. Chem. 239 (1964) 2580-2586.

[EC created 1972]

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