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4)acetylglucosaminide α23-sialyltransferase; α23 sialyltransferase
Reaction: CMP-N-acetylneuraminate + β-D-galactosyl-(1→4)-N-acetyl-D-glucosaminyl-glycoprotein = CMP + α-N-acetylneuraminyl-(2→3)-β-D-galactosyl-(1→4)-N-acetyl-D-glucosaminyl-glycoprotein
Other name(s): sialyltransferase; cytidine monophosphoacetylneuraminate-β-galactosyl(14)acetylglucosaminide α23-sialyltransferase; α23 sialyltransferase
Systematic name: CMP-N-acetylneuraminate:β-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein α-2,3-N-acetylneuraminyltransferase
Comments: Acts on β-D-galactosyl-1,4-N-acetyl-D-glucosaminyl termini on glycoprotein.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 77537-85-0
References:
1. Van den Eijnden, D.H. and Schiphorst, W.E.C.M. Detection of β-galactosyl(14)N-acetylglucosaminide α(23)-sialyltransferase activity in fetal calf liver and other tissues. J. Biol. Chem. 256 (1981) 3159-3162. [PMID: 7204397]