IUBMB Enzyme Nomenclature

EC 2.5.1.26

Accepted name: alkylglycerone-phosphate synthase

Reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion

Other name(s): alkyldihydroxyacetonephosphate synthase; alkyldihydroxyacetone phosphate synthetase; alkyl DHAP synthetase; alkyl-DHAP; dihydroxyacetone-phosphate acyltransferase; DHAP-AT

Systematic name: 1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase

Comments: The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 64060-42-0 and 102484-74-2

References:

1. Brown, A.J. and Snyder, F. Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism. J. Biol. Chem. 257 (1982) 8835-8839. [PMID: 7096336]

2. Wykle, R.L., Piantadosi, C. and Snyder, F. The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor. J. Biol. Chem. 247 (1972) 2944-2948. [PMID: 4401994]

[EC 2.5.1.26 created 1984]


Return to EC 2.5.1 home page
Return to EC 2.5 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page