IUBMB Enzyme Nomenclature


Accepted name: adenylate dimethylallyltransferase

Reaction: dimethylallyl diphosphate + AMP = diphosphate + N6-(dimethylallyl)adenosine 5′-phosphate

For diagram of reaction, click here

Other name(s): cytokinin synthase (ambiguous); isopentenyltransferase (ambiguous); 2-isopentenyl-diphosphate:AMP Δ2-isopentenyltransferase; adenylate isopentenyltransferase (ambiguous); IPT; adenylate dimethylallyltransferase

Systematic name: dimethylallyl-diphosphate:AMP dimethylallyltransferase

Comments: Involved in the biosynthesis of cytokinins in plants. Some isoforms from the plant Arabidopsis thaliana are specific for AMP while others also have the activity of EC, adenylate dimethylallyltransferase (ADP/ATP-dependent).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 72840-95-0


1. Chen, C.-M. and Melitz, D.K. Cytokinin biosynthesis in a cell-free system from cytokinin-autotrophic tobacco tissue cultures. FEBS Lett. 107 (1979) 15-20. [PMID: 499537]

2. Takei, K., Sakakibara, H. and Sugiyama, T. Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana. J. Biol. Chem. 276 (2001) 26405-26410. [PMID: 11313355]

3. Sakano, Y., Okada, Y., Matsunaga, A., Suwama, T., Kaneko, T., Ito, K., Noguchi, H. and Abe, I. Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.). Phytochemistry 65 (2004) 2439-2446. [PMID: 15381407]

[EC created 1984, modified 2002, modified 2013]

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