Reaction: S-adenosylmethioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+
Glossary: thermospermine = N1-[3-(3-aminopropylamino)propyl]butane-1,4-diamine
Other name(s): TSPMS; ACL5; SAC51
Systematic name: S-adenosylmethioninamine:spermidine 3-aminopropyltransferase (thermospermine synthesizing)
Comments: This enzyme is required for correct xylem specification through regulation of the lifetime of the xylem elements [3].
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
References:
1. Romer, P., Faltermeier, A., Mertins, V., Gedrange, T., Mai, R. and Proff, P. Investigations about N-aminopropyl transferases probably involved in biomineralization. J. Physiol. Pharmacol. 59 Suppl 5 (2008) 27-37. [PMID: 19075322]
2. Knott, J.M., Romer, P. and Sumper, M. Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine. FEBS Lett. 581 (2007) 3081-3086. [PMID: 17560575]
3. Muniz, L., Minguet, E.G., Singh, S.K., Pesquet, E., Vera-Sirera, F., Moreau-Courtois, C.L., Carbonell, J., Blazquez, M.A. and Tuominen, H. ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death. Development 135 (2008) 2573-2582. [PMID: 18599510]