IUBMB Enzyme Nomenclature


Accepted name: alanine—oxo-acid transaminase

Reaction: L-alanine + a 2-oxo carboxylate = pyruvate + an L-amino acid

For diagram click here (mechanism).

Other name(s): L-alanine-α-keto acid aminotransferase; leucine-alanine transaminase; alanine-keto acid aminotransferase; alanine-oxo acid aminotransferase

Systematic name: L-alanine:2-oxo-acid aminotransferase

Comments: A pyridoxal-phosphate protein.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9030-41-5


1. Altenbern, R.A. and Housewright, R.D. Transaminases in smooth Brucella abortus, strain 19. J. Biol. Chem. 204 (1953) 159-167.

2. Rowsell, E.V. Transaminations with pyruvate and other α-keto acids. Biochem. J. 64 (1956) 246-252.

3. Sallach, H.J. Formation of serine from hydroxypyruvate and L-alanine. J. Biol. Chem. 223 (1956) 1101-1108.

4. Wilson, D.G., King, K.W. and Burris, R.H. Transaminase reactions in plants. J. Biol. Chem. 208 (1954) 863-874.

[EC created 1961]

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