Reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
For diagram click here.
Other name(s): β-alanine—oxoglutarate transaminase; aminobutyrate aminotransferase; β-alanine aminotransferase; β-alanine-oxoglutarate aminotransferase; γ-aminobutyrate aminotransaminase; γ-aminobutyrate transaminase; γ-aminobutyrate-α-ketoglutarate aminotransferase; γ-aminobutyrate-α-ketoglutarate transaminase; γ-aminobutyrate:α-oxoglutarate aminotransferase; γ-aminobutyric acid aminotransferase; γ-aminobutyric acid pyruvate transaminase; γ-aminobutyric acid transaminase; γ-aminobutyric acid-α-ketoglutarate transaminase; γ-aminobutyric acid-α-ketoglutaric acid aminotransferase; γ-aminobutyric acid-2-oxoglutarate transaminase; γ-aminobutyric transaminase; 4-aminobutyrate aminotransferase; 4-aminobutyrate-2-ketoglutarate aminotransferase; 4-aminobutyrate-2-oxoglutarate aminotransferase; 4-aminobutyrate-2-oxoglutarate transaminase; 4-aminobutyric acid 2-ketoglutaric acid aminotransferase; 4-aminobutyric acid aminotransferase; aminobutyrate aminotransferase; aminobutyrate transaminase; GABA aminotransferase; GABA transaminase; GABA transferase; GABA-α-ketoglutarate aminotransferase; GABA-α-ketoglutarate transaminase; GABA-α-ketoglutaric acid transaminase; GABA-α-oxoglutarate aminotransferase; GABA-2-oxoglutarate aminotransferase; GABA-2-oxoglutarate transaminase; GABA-oxoglutarate aminotransferase; GABA-oxoglutarate transaminase; glutamate-succinic semialdehyde transaminase; GabT
Systematic name: 4-aminobutanoate:2-oxoglutarate aminotransferase
Comments: Some preparations also act on β-alanine, 5-aminopentanoate and (R,S)-3-amino-2-methylpropanoate.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, PDB, CAS registry number: 9037-67-6
References:
1. Aurich, H. Über die β-Alanin-α-Ketoglutarat-Transaminase aus Neurospora crassa. Hoppe-Seyler's Z. Physiol. Chem. 326 (1961) 25-33.
2. Schausboe, A., Wu, J.-Y. and Roberts, E. Purification and characterization of the 4-aminobutyrate-2,ketoglutarate transaminase from mouse brain. Biochemistry 12 (1973) 2868-2873. [PMID: 4719123]
3. Scott, E.M. and Jakoby, W.B. Soluble γ-aminobutyric-glutamic transaminase from Pseudomonas fluorescens. J. Biol. Chem. 234 (1959) 932-936. [PMID: 13654294]