IUBMB Enzyme Nomenclature

EC 2.6.1.43

Accepted name: aminolevulinate transaminase

Reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine

Other name(s): aminolevulinate aminotransferase, γ,δ-dioxovalerate aminotransferase; γ,δ-dioxovaleric acid transaminase; 4,5-dioxovalerate aminotransferase; 4,5-dioxovaleric acid transaminase; 4,5-dioxovaleric transaminase; 5-aminolevulinic acid transaminase; alanine-γ,δ-dioxovalerate aminotransferase; alanine-dioxovalerate aminotransferase; alanine:4,5-dioxovalerate aminotransferase; aminolevulinic acid transaminase; dioxovalerate transaminase; L-alanine-4,5-dioxovalerate aminotransferase; L-alanine:4,5-dioxovaleric acid transaminase; L-alanine:dioxovalerate transaminase; DOVA transaminase; 4,5-dioxovaleric acid aminotransferase

Systematic name: 5-aminolevulinate:pyruvate aminotransferase

Comments: A pyridoxal-phosphate protein.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9012-46-8

References:

1. Gibson, K.D., Matthew, M. and Neuberger, A. Biosynthesis of porphyrins and chlorophylls. Nature 192 (1961) 204-208.

2. Neuberger, A. and Turner, J.M. γ,δ-Dioxovalerate aminotransferase activity in Rhodopseudomonas spheroides. Biochim. Biophys. Acta 67 (1963) 342-345.

[EC 2.6.1.43 created 1972]


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