IUBMB Enzyme Nomenclature


Accepted name: dihydroxyphenylalanine transaminase

Reaction: 3,4-dihydroxy-L-phenylalanine + 2-oxoglutarate = 3,4-dihydroxyphenylpyruvate + L-glutamate

For diagram click here (mechanism).

Glossary: L-dopa = 3,4-dihydroxy-L-phenylalanine

Other name(s): dopa transaminase; dihydroxyphenylalanine aminotransferase; aspartate-DOPP transaminase (ADT); L-dopa transaminase; dopa aminotransferase; glutamate-DOPP transaminase (GDT); phenylalanine-DOPP transaminase (PDT); DOPA 2-oxoglutarate aminotransferase; DOPAATS

Systematic name: 3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase

Comments: A pyridoxal-phosphate protein.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37277-98-8


1. Fonnum, F. and Larsen, K. Purification and properties of dihydroxyphenylalanine transaminase from guinea pig brain. J. Neurochem. 12 (1965) 589-598. [PMID: 5829872]

2. Ranjith, N.K., Sasikala, Ch. and Ramana, Ch.V. Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine. Res. Microbiol. 158 (2007) 506-511. [PMID: 17616348]

[EC created 1972]

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