Reaction: An aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate
For diagram click here or here.
Other name(s): aromatic amino acid aminotransferase; aromatic aminotransferase; ArAT
Systematic name: aromatic-amino-acid:2-oxoglutarate aminotransferase
Comments: A pyridoxal-phosphate protein. L-Methionine can also act as donor, but more slowly; oxaloacetate can act as acceptor. Controlled proteolysis converts the enzyme into EC 220.127.116.11 aspartate transaminase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37332-38-0
1. Mavrides, C. and Orr, W. Multispecific aspartate and aromatic amino acid aminotransferases in Escherichia coli. J. Biol. Chem. 250 (1975) 4128-4133. [PMID: 236311]