IUBMB Enzyme Nomenclature


Accepted name: glutamine—phenylpyruvate transaminase

Reaction: L-glutamine + phenylpyruvate = 2-oxoglutaramate + L-phenylalanine

For diagram click here (mechanism).

Other name(s): glutamine transaminase K; glutamine-phenylpyruvate aminotransferase

Systematic name: L-glutamine:phenylpyruvate aminotransferase

Comments: A pyridoxal-phosphate protein. L-Methionine, L-histidine and L-tyrosine can act as donors. The enzyme has little activity on pyruvate and glyoxylate (cf. EC glutamine—pyruvate transaminase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 68518-06-9


1. Cooper, A.J.L. Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and α-keto-γ-methiolbutyrate. Anal. Biochem. 89 (1978) 451-460. [PMID: 727444]

2. Cooper, A.J.L. and Meister, A. Isolation and properties of a new glutamine transaminase from rat kidney. J. Biol. Chem. 249 (1974) 2554-2561. [PMID: 4822504]

[EC created 1984]

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