Reaction: L-glutamine + phenylpyruvate = 2-oxoglutaramate + L-phenylalanine
For diagram click here (mechanism).
Other name(s): glutamine transaminase K; glutamine-phenylpyruvate aminotransferase
Systematic name: L-glutamine:phenylpyruvate aminotransferase
Comments: A pyridoxal-phosphate protein. L-Methionine, L-histidine and L-tyrosine can act as donors. The enzyme has little activity on pyruvate and glyoxylate (cf. EC 220.127.116.11 glutaminepyruvate transaminase).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 68518-06-9
1. Cooper, A.J.L. Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and α-keto-γ-methiolbutyrate. Anal. Biochem. 89 (1978) 451-460. [PMID: 727444]
2. Cooper, A.J.L. and Meister, A. Isolation and properties of a new glutamine transaminase from rat kidney. J. Biol. Chem. 249 (1974) 2554-2561. [PMID: 4822504]