Reaction: ATP + β-D-fructose 6-phosphate = ADP + β-D-fructose 2,6-bisphosphate
Other name(s): phosphofructokinase 2; 6-phosphofructose 2-kinase; 6-phosphofructo-2-kinase (phosphorylating); fructose 6-phosphate 2-kinase; ATP:D-fructose-6-phosphate 2-phosphotransferase
Systematic name: ATP:β-D-fructose-6-phosphate 2-phosphotransferase
Comments: Not identical with EC 220.127.116.11 6-phosphofructokinase. The enzyme co-purifies with EC 18.104.22.168 fructose-2,6-bisphosphate 2-phosphatase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 78689-77-7
1. Van Schaftingen, E. and Hers, H.-G. Phosphofructokinase 2: the enzyme that forms fructose 2,6-bisphosphate from fructose 6-phosphate and ATP. Biochem. Biophys. Res. Commun. 107 (1981) 1078-1084. [PMID: 6458291]